6-METHOXYPYRIDINE-2-CARBOXYLIC ACID

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Table of Contents

1. Product Information & Specifications

Chemical Profile

Parameter Specification
CAS Number 108911-35-1
Molecular Formula C7H7NO3
Molecular Weight 153.14 g/mol
Appearance White to off-white crystalline powder
Purity (HPLC) >98%
Melting Point 192-195°C
Solubility Soluble in DMSO, methanol; slightly soluble in water

Comparative Analysis

Feature 6-Methoxy Analog Pyridine-2-carboxylic Acid
Reactivity Enhanced electron density Standard reactivity
Bioavailability Improved membrane permeability Lower absorption rates
Pharma Applications Kinase inhibitor synthesis General intermediate

2. Key Applications & Industrial Uses

Pharmaceutical Development

Critical intermediate for:

  • JAK/STAT pathway inhibitors
  • Anticancer prodrug synthesis
  • Neuroprotective agent development

Agrochemical Formulations

  • Herbicide metabolite synthesis
  • Fungicidal compound modification

Advanced Material Science

  • Coordination polymer synthesis
  • Luminescent material precursors

3. Operational Guidelines

Storage Protocols

  • Maintain at 2-8°C in sealed container
  • Desiccate (RH <40%)

Reaction Handling

  • Use under nitrogen atmosphere
  • Optimal solvent: anhydrous DMF
  • Stoichiometric range: 1.2-1.5 eq

4. Industry Case Studies

Case 1: Oncology Drug Development

Client: Top 10 Pharma Company (Confidential)

  • Application: Bruton’s tyrosine kinase (BTK) inhibitor intermediate
  • Result: 22% yield improvement vs traditional routes
  • Scale: 150kg pilot production

Case 2: Next-Gen Herbicides

Client: EU Agrochem Leader

  • Application: Chloroacetanilide herbicide modification
  • Outcome: 40% reduction in aquatic toxicity
  • Commercial Status: EPA Stage III review

5. Request Customized Solutions

Explore tailored specifications:

  • Custom purity grades (98-99.9%)
  • Bulk quantities (100kg+)
  • GMP-compliant synthesis

Contact our technical team:
Email: info@vivalr.com
Tel: (86) 15866781826

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