Table of Contents
1,1,3,3-Tetramethylguanidine (CAS 80-70-6): Technical Specifications
Basic Properties
| Parameter |
Specification |
| Chemical Name |
1,1,3,3-Tetramethylguanidine |
| CAS Number |
80-70-6 |
| Molecular Formula |
C5H13N3 |
| Molecular Weight |
115.18 g/mol |
| Appearance |
Colorless to pale yellow liquid |
| Purity |
≥99% (GC analysis) |
| Density |
0.92 g/cm³ at 20°C |
| Boiling Point |
160-162°C |
Performance Comparison
| Feature |
TMG |
DBU |
MTBD |
| Basicity (pKa) |
13.5 |
11.5 |
14.0 |
| Reaction Speed |
Fast |
Moderate |
Very Fast |
| Thermal Stability |
Excellent |
Good |
Excellent |
| Price Competitiveness |
$$ |
$$$ |
$$$$ |
2. Industrial Applications & Functional Advantages
Pharmaceutical Synthesis
Preferred catalyst for nucleophilic substitution reactions in API production, particularly effective in:
- Beta-lactam antibiotic synthesis
- Heterocyclic compound formation
- Peptide coupling reactions
Polymer Chemistry
- Polyurethane catalyst showing 40% faster curing vs conventional amines
- Epoxy resin modifier enhancing thermal resistance
3. Documented Client Implementations
Case 1: Pharmaceutical Intermediate Production
| Client |
Top 10 EU Pharma Manufacturer |
| Challenge |
Low yield (58%) in cephalosporin intermediate synthesis |
| Solution |
0.8mol% TMG catalyst system |
| Result |
Yield increased to 89% with 99.2% purity |
Case 2: Specialty Adhesive Development
| Client |
US Aerospace Materials Supplier |
| Application |
High-temperature polyimide adhesives |
| Benefit |
Enabled 300°C operational stability |
| Volume |
2.5MT annual consumption |
4. Safety & Regulatory Compliance
| Aspect |
Requirement |
| Storage |
Nitrogen atmosphere, <25°C |
| PPE |
Chemical goggles + neoprene gloves |
| Spill Management |
Absorb with vermiculite, pH neutralization |
| Transport |
UN2922 Corrosive liquid, toxic |
5. Technical Consultation & Ordering
Contact our chemical engineers for application-specific guidance:
Email: info@vivalr.com
Tel: (86) 15866781826
Request:
- Custom purity specifications (99.5%-99.99%)
- Bulk packaging solutions (200kg drums to ISO tanks)
- REACH-compliant documentation
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