Table of Contents
- Product Overview
- Specifications & Comparison
- Key Applications
- Usage Guidelines
- Industry Case Studies
- Contact for Technical Consultation
Calcium Citrate (CAS 5785-44-4) Product Overview
| Parameter | Specification |
|---|---|
| Chemical Name | Calcium Citrate Tetrahydrate |
| CAS Number | 5785-44-4 |
| Molecular Formula | Ca₃(C₆H₅O₇)₂·4H₂O |
| Appearance | White crystalline powder |
| Calcium Content | 20-24% |
| Solubility | 1g/100ml cold water |
| pH Value | 6.0-8.0 (5% solution) |
| Heavy Metals | ≤10ppm |
| Loss on Drying | 10-13% |
| Certifications | USP, FCC, ISO 9001 |
Comparative Analysis of Calcium Salts
| Property | Calcium Citrate | Calcium Carbonate | Calcium Lactate |
|---|---|---|---|
| Elemental Calcium | 21% | 40% | 13% |
| Absorption Rate | 35-40% | 25-30% | 28-32% |
| Acid Requirement | None | High | Moderate |
| GI Tolerance | Excellent | Poor | Good |
| pH Stability | 2.5-7.5 | >5.5 | 3.0-8.0 |
| Cost Efficiency | Medium | High | Low |
Industrial & Nutritional Applications
1. Dietary Supplements
Preferred calcium source for:
- Prenatal vitamins (superior absorption)
- Senior formulations (reduced acid dependency)
- Vegan products (plant-based compatibility)
2. Food Fortification
- Juice beverages (pH stability)
- Bakery products (heat resistance)
- Dairy alternatives (calcium enrichment)
3. Pharmaceutical Uses
- Antacid formulations
- Osteoporosis treatments
- Calcium deficiency therapy
4. Industrial Applications
- Water treatment chelating agent
- Cosmetic stabilizer
- Biodegradable plastics additive
Technical Implementation Guidelines
Optimal Usage Parameters
| Application | Dosage | Processing Temp | Compatibility |
|---|---|---|---|
| Tableting | 300-600mg | ≤60°C | Starch, MCC |
| Liquids | 1-2% w/v | RT | Citric acid, Xanthan |
| Food Processing | 0.5-1.5% | 40-80°C | Soy, Gluten-free |
Stability Considerations
- Humidity: Maintain below 65% RH
- Light: Protect from direct sunlight
- Shelf Life: 36 months in sealed containers
Documented Success Cases
Case 1: Nutraceutical Manufacturer (Germany)
Challenge: Reformulate calcium supplements for improved bioavailability
Solution: 500mg Calcium Citrate with Vitamin D3 complex
Result: 42% absorption increase vs. carbonate form
Case 2: Asian Beverage Company
Challenge: Calcium fortification without precipitation
Solution: 0.8% Calcium Citrate + citrate buffer system
Result: Stable 12-month shelf life in acidic drinks
Case 3: US Pharmaceutical Leader
Challenge: Develop geriatric-friendly antacid
Solution: Calcium Citrate-based chewable tablets
Result: 78% reduction in GI complaints vs. carbonate
Technical Consultation & Ordering
For formulation support or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Why Choose Our Calcium Citrate?
- Batch-to-batch consistency (ISO certified)
- Custom particle sizes (50-300μm available)
- Documented regulatory support (FDA DMF #023157)



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