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Specialized in1-Hexadecylamine CAS 143-27-1and related product development and production

Chemical Name: 1-Hexadecylamine
Synonyms 1-Aminohexadecane; Hexyldecylamine; n-Certylamine
CAS No.: 143-27-1
Molecular Formula: C16H35N
Molecular Weight: 241.46
Appearance: White Crystal

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

1-Hexadecylamine (CAS 143-27-1) Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

1-Hexadecylamine (CAS 143-27-1), also known as cetrimonium amine, is a long-chain primary amine widely used in industrial chemistry. Key parameters:

Parameter Value
Chemical Formula C16H35N
Molecular Weight 241.46 g/mol
Appearance White crystalline solid
Purity ≥98% (GC analysis)
Melting Point 46-49°C
Solubility Insoluble in water, soluble in ethanol/chloroform
Storage 2-8°C in airtight container

2. Key Applications & Industrial Uses

Core Functional Areas:

  • Surfactant Intermediate: Cationic precursor for quaternary ammonium compounds
  • Corrosion Inhibition: Metal surface treatment in acidic environments
  • Pharmaceuticals: Drug delivery vector in lipid nanoparticle formulations
  • Cosmetic Chemistry: Emulsion stabilizer in hair conditioners
  • Agrochemicals: Adjuvant for pesticide formulations
  • Petroleum Additives: Friction modifier in lubricant packages

3. Performance Comparison with Similar Amines

Parameter Hexadecylamine Octadecylamine Tetradecylamine
Carbon Chain C16 C18 C14
Melting Point 46-49°C 53-56°C 38-41°C
Surface Tension 32 mN/m 29 mN/m 35 mN/m
Krafft Temperature 45°C 50°C 40°C
Cost Efficiency ★★★★☆ ★★★☆☆ ★★★★★

4. Operational Guidelines & Safety Protocols

Handling Requirements:

  • Use NIOSH-approved respirator when handling powder form
  • Maintain ventilation rates ≥15 CFM/sq.ft in processing areas
  • Ground all equipment to prevent static discharge

Storage Compatibility:

  • Incompatible with strong oxidizers, acids, and halogenated compounds
  • Maximum stacking height: 1.8 meters in palletized storage

5. Verified Customer Case Studies

Case 1: Pharmaceutical Delivery System Enhancement

Client: European mRNA Vaccine Producer
Challenge: Required stable lipid nanoparticles with >80% encapsulation efficiency
Solution: Optimized 1-Hexadecylamine concentration at 0.8 mol% in lipid matrix
Outcome: Achieved 92% encapsulation with 6-month stability at 2-8°C

Case 2: Industrial Corrosion Inhibition

Client: Gulf Coast Oil Refinery
Challenge: Reduce pipeline corrosion rates from 0.8 mm/yr to <0.2 mm/yr
Solution: 200 ppm Hexadecylamine-based inhibitor in recirculating system
Outcome: 0.15 mm/yr corrosion rate achieved, extending maintenance intervals by 300%

6. Request Customized Solutions

For technical specifications, bulk pricing, or formulation assistance:

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

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FAQ

Does it support auditing?

Support, please make an appointment one day in advance. Company address: Room 716, Building 3, Ligao International Garden, No.1222 West Aoti Road, Lixia District, Jinan City, Shandong Province, P.R. China

Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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