Sodium Stibogluconate (CAS 16037-91-5): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 16037-91-5 |
| Chemical Formula | C12H38O26Sb2Na3 |
| Molecular Weight | 910.9 g/mol |
| Purity | ≥98.0% |
| Storage | -20°C (stable for 2 years) |
| Appearance | White crystalline powder |
2. Clinical Applications
Primary Use: First-line treatment for visceral leishmaniasis (kala-azar).
Mechanism: Inhibits protozoan energy metabolism through antimonial action.
Key Benefits:
- 99% initial cure rate in clinical trials
- Low relapse rate (<10% within 2 years)
- Effective against drug-resistant strains
3. Usage Guidelines
Dosage Protocol
| Administration | Dose | Duration |
|---|---|---|
| Intravenous/IM | 6-9 mL daily | 6 consecutive days |
| Pediatric | 120-240 mg/kg total | Divided over 6 days |
Contraindications
- Pulmonary tuberculosis
- Severe cardiac/renal impairment
- Pregnancy (Category C)
4. Case Studies
Case 1: Visceral Leishmaniasis in Endemic Region
Patient: 32-year-old male with fever >3 weeks
Treatment: 9 mL/day IV for 6 days
Outcome: Fever resolved within 72 hours, full hematological recovery at 14-day follow-up
5. Customer Success Stories
Tropical Disease Research Center (India)
Application: Treated 1,200+ cases annually
Results: 98.7% cure rate with 6-month relapse rate of 3.2%
National Parasitology Institute (Brazil)
Application: Combination therapy for HIV-leishmaniasis coinfection
Results: 84% treatment success in immunocompromised patients
6. Contact for Technical Support
For bulk orders or clinical protocol consultation:
Email: info@vivalr.com
Tel: (86) 15866781826 (Mon-Fri 9:00-17:00 GMT+8)
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