Dehydrocholic acid CAS 81-23-2

Chemical Name: Dehydrocholic acid
Synonyms: Acide dehydrocholique; Triketocholanic acid
CAS No.: 81-23-2
Molecular Formula: C24H34O5
Molecular Weight: 402.53
Appearance: Powder

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Comprehensive Guide to Dehydrocholic Acid (CAS 81-23-2)

Table of Contents

1. Basic Information & Specifications

Parameter Value
CAS Number 81-23-2
Molecular Formula C24H34O5
Molecular Weight 402.52 g/mol
Appearance White to off-white crystalline powder
Melting Point 238-240°C
Boiling Point 581.5°C at 760 mmHg
Density 1.2±0.1 g/cm³
Solubility 65 mg/L in water (30°C), ethanol: 10 mg/mL

2. Detailed Applications

Medical Applications

• Treatment of chronic cholecystitis and cholelithiasis
• Post-surgical biliary drainage enhancement
• Management of bile duct dysfunction and constipation

Pharmaceutical Research

• Intermediate in steroid-based drug synthesis
• Reference standard for analytical testing

Contraindications

• Complete biliary obstruction
• Severe hepatic/renal impairment
• Pediatric patients under 12 years

3. Safety & Handling Guidelines

Hazard Class Precautionary Measures
Acute Toxicity (Oral, Category 5) Use PPE; avoid inhalation/ingestion
Storage 2-8°C in sealed container
First Aid Flush eyes/skin with water; seek medical attention if ingested

4. Industry Case Studies

Case 1: Pharmaceutical Manufacturing

A Shanghai-based API producer achieved 99.2% purity through optimized crystallization, complying with USP 43 standards.

Case 2: Research Institution Application

University researchers utilized dehydrocholic acid as a choleretic agent in hepatoprotective drug development studies.

5. Procurement Guidance

Supplier Purity Packaging
Acmec Biochemical ≥98.5% 100mg-1kg
Yuanye Bio-Tech HPLC Grade 10g-500g

6. Contact for Technical Support

For analytical certificates, bulk pricing, or formulation assistance:
Email: info@vivalr.com
Tel: (86) 15866781826

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