L-Tryptophan (CAS 73-22-3) Comprehensive User Guide

1. Product Specifications & Comparative Analysis

2. Functional Applications

Core Biological Functions

• Precursor to serotonin (5-HT) and melatonin synthesis
• Essential component for vitamin B₃ (niacin) production
• Modulator of cellular proliferation cycles (G1 phase regulation)

Research Applications

• In Vitro: Demonstrated 48-hour inhibition of pTr2 cell proliferation at 500-1000 μM concentrations
• Stem Cell Research: Enhances hBMSC migration (10 μM) and osteogenic differentiation
• Material Science: Base compound for functionalized derivatives (e.g., L-Tryptophan-N₃)

3. Implementation Scenarios

Pharmaceutical Development

• Neurotransmitter modulation therapies
• Bone regeneration accelerants (50 mg/kg/day efficacy in murine models)

Biotechnology Applications

• Fluorescent probes (Rhodamine B conjugates)
• Targeted drug delivery systems

4. Client Success Stories

Case Study 1: Biomedical Research Institute

• Application: Osteoporosis treatment development
• Result: 40% acceleration in bone defect recovery using 50 mg/kg/day dosage

Case Study 2: Neuropharmacology Laboratory

• Application: Serotonin pathway analysis
• Outcome: Identified novel depression treatment targets

5. Operational Guidelines

Safety Protocols

• Maintain nitrogen atmosphere during long-term storage
• Use amber glass containers for light sensitivity

Regulatory Compliance

• For research use only (non-diagnostic/non-therapeutic applications)
• Material Safety Data Sheet (MSDS) required for transport