Table of Contents
- Product Overview
- Key Parameters & Comparative Analysis
- Applications & Use Cases
- Client Case Studies
- Request Quotation
Milbemycin Oxime (CAS 129496-10-2) Overview
Basic Specifications
| Parameter | Description |
|---|---|
| Chemical Name | Milbemycin Oxime |
| CAS Number | 129496-10-2 |
| Molecular Formula | C₃₁H₄₃NO₇ |
| Molecular Weight | 541.68 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in organic solvents (e.g., ethanol, DMSO), insoluble in water |
| Storage | 2-8°C in airtight container, protected from light |
Regulatory Status
- EPA Registration: Approved for veterinary and agricultural use
- GMP Certification: Compliant with FDA 21 CFR §211
- REACH Registered: Yes (EC 603-123-8)
Technical Parameters & Comparative Analysis
| Feature | Milbemycin Oxime | Ivermectin | Spinosad |
|---|---|---|---|
| Mode of Action | Glutamate-gated chloride channel activator | GABA receptor agonist | Nicotinic acetylcholine receptor activator |
| Spectrum | Nematodes, arthropods | Broad-spectrum antiparasitic | Lepidoptera, Thysanoptera |
| Mammalian Safety | LD50 >2,000 mg/kg (rat) | LD50 40 mg/kg (rat) | LD50 3,783 mg/kg (rat) |
| Half-life | 9-13 days (canine) | 18 hours (bovine) | 1-2 days (soil) |
| Price per kg | $1,200-$1,500 | $800-$1,000 | $2,000-$2,500 |
Primary Applications & Implementation
Veterinary Medicine
- Canine heartworm prevention: 0.5 mg/kg monthly dosage
- Treatment of demodectic mange: 2 mg/kg weekly for 4 weeks
- Broad-spectrum parasite control in livestock
Agricultural Use
- Nematicide for root-knot nematodes: 50-100 g/hectare
- Integrated Pest Management (IPM) in citrus orchards
- Turf protection against white grubs
Pharmaceutical Formulations
- Chewable tablets for dogs (e.g., Interceptor® Flavor Tabs)
- Injectable solutions for cattle
- Water-dispersible granules for crop spraying
Documented Client Success Stories
Case 1: US Animal Health Company
- Client: Top 3 veterinary pharmaceutical manufacturer
- Challenge: Needed stable API for heartworm prevention medication
- Solution: Supplied 98.7% pure Milbemycin Oxime with ICH stability data
- Outcome: Achieved 12-month shelf life at 25°C/60% RH
Case 2: Chinese Veterinary Drug Producer
- Client: Emerging generic animal health company
- Challenge: Required cost-effective API for combination products
- Solution: Provided GMP-certified bulk material with 3% price advantage
- Outcome: Launched lufenuron + milbemycin oxime combo in 8 months
Case 3: Indian Agrochem Enterprise
- Client: Export-oriented crop protection formulator
- Challenge: Sought resistance management solution for nematodes
- Solution: Developed 5% EC formulation with enhanced bioavailability
- Outcome: 92% control efficacy in banana plantations vs. traditional methods
Request Product Specifications & Pricing
For technical documents, COA, or customized formulations:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Our advantages:
- ISO 9001:2015 certified production
- Batch-to-batch consistency guaranteed
- Custom particle size distribution (5-50μm)
- MOQ: 1kg (R&D samples available)



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