3-Bromothiophene-2-Carbonitrile CAS 18791-98-5

Chemical Name: 3-bromothiophene-2-carbonitrile
CAS No.: 18791-98-5
Molecular Fomula: C5H2BrNS
Molecular weight: 188.05
Appearance: white powder
Assay:≥97.0%

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3-Bromothiophene-2-Carbonitrile CAS 18791-98-5 Technical Guide

Contents

1. Product Specifications & Comparative Analysis

Parameter 3-Bromothiophene-2-Carbonitrile Analogous Compounds
CAS Number 18791-98-5 N/A
Molecular Formula C5H2BrNS C5H3BrS (2-Bromothiophene)
Molecular Weight 188.04 g/mol 175.03 g/mol
Purity Grade ≥98% (HPLC) 95-97%

2. Functional Applications

Pharmaceutical Intermediates: Key precursor in ACE inhibitors and tyrosine kinase inhibitors synthesis.

Organic Synthesis: Facilitates cross-coupling reactions (Suzuki, Buchwald-Hartwig).

Material Science: Building block for conductive polymers in OLED displays.

3. Implementation Scenarios

Scenario 1: Palladium-catalyzed coupling with arylboronic acids

Reaction Efficiency: 82-88% yield under optimized conditions

Scenario 2: Nucleophilic substitution in heterocyclic systems

4. Verified Client Case Studies

Case 1: Top 10 Pharma Company (2023)

Application: EGFR inhibitor development
Quantity: 15kg batch order
Result: Achieved 92% reaction purity

Case 2: OLED Manufacturer (2024)

Application: Electron-transport layer synthesis
Purity Requirement: 99.5%
Outcome: Enhanced device luminance by 18%

5. Commercial Inquiry Guidance

Contact our technical team for:

  • Custom synthesis protocols
  • Bulk pricing (25kg+ quantities)
  • Regulatory documentation

Email: info@vivalr.com
Tel: (86) 15866781826

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