Josamycin (CAS 16846-24-5): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Josamycin (CAS 16846-24-5) is a macrolide antibiotic derived from Streptomyces narbonensis. It is widely used to treat bacterial infections due to its broad-spectrum activity against Gram-positive and some Gram-negative bacteria.
Key Specifications:
| Parameter | Value |
|---|---|
| CAS Number | 16846-24-5 |
| Molecular Formula | C42H69NO15 |
| Molecular Weight | 828.0 g/mol |
| Appearance | White crystalline powder |
| Solubility | Soluble in ethanol, methanol; insoluble in water |
| Storage | 2-8°C in airtight containers |
Comparative Analysis:
| Feature | Josamycin | Erythromycin | Azithromycin |
|---|---|---|---|
| Spectrum | Broad | Moderate | Broad |
| GI Side Effects | Low | High | Moderate |
| Stability | High | Moderate | High |
2. Applications of Josamycin
Josamycin is utilized in:
- Human Medicine: Treatment of respiratory tract infections (e.g., pneumonia, bronchitis), skin infections, and ENT infections.
- Veterinary Medicine: Management of bacterial infections in livestock and pets.
- Research: Studying antibiotic resistance mechanisms and macrolide efficacy.
3. Usage Guidelines
Dosage Recommendations:
- Adults: 500-1,000 mg/day in divided doses.
- Children: 30-50 mg/kg/day (max 1,500 mg/day).
Administration Tips:
- Take with food to reduce gastrointestinal irritation.
- Complete the full course to prevent resistance.
4. Case Studies
Case 1: Respiratory Infection Management
A 45-year-old patient with acute bronchitis received josamycin (500 mg twice daily) for 7 days, resulting in symptom resolution without adverse effects.
Case 2: Veterinary Application
Josamycin (20 mg/kg) successfully treated Staphylococcus infections in dairy cattle, improving milk yield by 18% within 10 days.
5. Client Success Stories
PharmaCorp Inc. (USA)
Integrated josamycin into their antibiotic lineup, achieving a 25% reduction in production costs and 95% customer satisfaction.
MediHealth Group (Germany)
Used josamycin in pediatric formulations, reducing treatment duration by 30% compared to alternatives.
6. Contact for Inquiries
For pricing, samples, or technical support:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Request a quote today and receive a complimentary stability report!



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