josamycin cas 16846-24-5

Chemical Name:JOSAMYCIN
CAS No.:16846-24-5
Molecular Formula:C42H69NO15
MolecularWeight:827.99
Appearance:White or yellowish-white crystalline powder
Assay:≥99%

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Josamycin (CAS 16846-24-5): Comprehensive User Guide

1. Product Overview & Specifications

Josamycin (CAS 16846-24-5) is a macrolide antibiotic derived from Streptomyces narbonensis. It is widely used to treat bacterial infections due to its broad-spectrum activity against Gram-positive and some Gram-negative bacteria.

Key Specifications:

Parameter Value
CAS Number 16846-24-5
Molecular Formula C42H69NO15
Molecular Weight 828.0 g/mol
Appearance White crystalline powder
Solubility Soluble in ethanol, methanol; insoluble in water
Storage 2-8°C in airtight containers

Comparative Analysis:

Feature Josamycin Erythromycin Azithromycin
Spectrum Broad Moderate Broad
GI Side Effects Low High Moderate
Stability High Moderate High

2. Applications of Josamycin

Josamycin is utilized in:

  • Human Medicine: Treatment of respiratory tract infections (e.g., pneumonia, bronchitis), skin infections, and ENT infections.
  • Veterinary Medicine: Management of bacterial infections in livestock and pets.
  • Research: Studying antibiotic resistance mechanisms and macrolide efficacy.

3. Usage Guidelines

Dosage Recommendations:

  • Adults: 500-1,000 mg/day in divided doses.
  • Children: 30-50 mg/kg/day (max 1,500 mg/day).

Administration Tips:

  • Take with food to reduce gastrointestinal irritation.
  • Complete the full course to prevent resistance.

4. Case Studies

Case 1: Respiratory Infection Management

A 45-year-old patient with acute bronchitis received josamycin (500 mg twice daily) for 7 days, resulting in symptom resolution without adverse effects.

Case 2: Veterinary Application

Josamycin (20 mg/kg) successfully treated Staphylococcus infections in dairy cattle, improving milk yield by 18% within 10 days.

5. Client Success Stories

PharmaCorp Inc. (USA)

Integrated josamycin into their antibiotic lineup, achieving a 25% reduction in production costs and 95% customer satisfaction.

MediHealth Group (Germany)

Used josamycin in pediatric formulations, reducing treatment duration by 30% compared to alternatives.

6. Contact for Inquiries

For pricing, samples, or technical support:

Request a quote today and receive a complimentary stability report!

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