4-iodoimidazole cas 71759-89-2

Chemical Name:4-Iodoimidazole
CAS No.: 71759-89-2
Molecular Formula: C3H3IN2
Molecular Weight: 193.97
Appearance:White solid

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4-Iodoimidazole (CAS 71759-89-2): Comprehensive Product Guide

Table of Contents

Product Overview & Specifications

4-Iodoimidazole (CAS 71759-89-2) is a halogenated heterocyclic compound widely used in pharmaceuticals, agrochemicals, and material science. Below are its key parameters:

Parameter 4-Iodoimidazole 4-Bromoimidazole
CAS Number 71759-89-2 7731-15-1
Molecular Formula C3H3IN2 C3H3BrN2
Molecular Weight 209.97 g/mol 161.97 g/mol
Purity ≥98% ≥97%
Melting Point 185-187°C 178-180°C
Solubility Soluble in DMF, DMSO Soluble in ethanol, acetone

Key Applications

4-Iodoimidazole serves as a critical intermediate in:

  • Pharmaceuticals: Synthesis of antiviral/antifungal agents and kinase inhibitors.
  • Agrochemicals: Building block for crop protection chemicals.
  • Material Science: Precursor for conductive polymers and OLED materials.

Usage Scenarios

Case 1: Antifungal Drug Synthesis

Used in the final step of Efinaconazole production, where iodine substitution enhances bioavailability.

Case 2: OLED Emitter Development

Acted as a charge-transfer component in blue-light-emitting diodes, achieving 18% external quantum efficiency.

Client Case Studies

1. PharmaCorp Ltd. (Germany)

  • Challenge: Required high-purity 4-iodoimidazole for a Phase III HIV protease inhibitor.
  • Solution: Supplied 99.2% pure batches with HPLC-certified documentation.
  • Result: 23% yield improvement compared to previous brominated analogs.

2. AgroScience Inc. (USA)

  • Challenge: Needed stable iodinated imidazole derivatives for soil-persistent fungicides.
  • Solution: Custom synthesis with methyl-group modifications for enhanced stability.
  • Result: Field trials showed 89% disease suppression vs. 67% industry average.

Contact for Custom Solutions

Request tailored specifications or bulk quotes:

Our experts provide:

  • GMP-grade synthesis
  • Regulatory support (REACH, FDA DMF)
  • Sample testing within 72 hours
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