1. Product Overview and Specifications

Niclosamide (CAS 50-65-7) is a chlorinated salicylanilide compound widely recognized for its anthelmintic and potential anticancer properties. Below are its key specifications:

Comparative Analysis with Similar Compounds

2. Key Applications and Uses

2.1 Antiparasitic Agent

Niclosamide is FDA-approved for treating tapeworm infections (e.g., Taenia saginata, Hymenolepis nana) by disrupting mitochondrial ATP production.

2.2 Agricultural Applications

Used as a molluscicide to control snail populations in aquaculture and agriculture, reducing parasitic disease transmission.

2.3 Cancer Research

Inhibits Wnt/β-catenin, mTOR, and STAT3 signaling pathways, showing efficacy against colorectal, prostate, and breast cancers in preclinical models.

3. Usage Guidelines and Best Practices

3.1 Pharmaceutical Formulations

• Oral tablets: 2 g single dose for tapeworms
• Combination therapies with albendazole for enhanced efficacy

3.2 Research Protocols

• Cell culture: 0.1-10 μM concentrations
• In vivo studies: 10-50 mg/kg/day (mouse models)

4. Case Studies

4.1 Tapeworm Eradication in Cattle

A Brazilian farm achieved 98% clearance of Taenia infections using niclosamide-impregnated feed over 12 weeks.

4.2 Snail Control in Rice Paddies

Vietnamese farmers reduced schistosomiasis vectors by 85% through monthly 0.25% niclosamide spraying.

5. Customer Success Stories

5.1 ABC Biopharma (USA)

Discovered niclosamide derivatives with 10x improved bioavailability for metastatic cancer trials.

5.2 AquaHealth Ltd. (Thailand)

Reduced shrimp pond snail populations by 92% using niclosamide pellets, increasing yield by 18%.

6. Contact for Inquiries

For pricing, samples, or technical support:

Email: info@vivalr.com
Phone: (86) 15866781826