side chain for meropenem cas 96034-64-9

Chemical Name: Side chain for meropenem
CAS No.: 96034-64-9
Molecular Formula: C15H19N3O5S
Molecular Weight: 353.40
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Meropenem Side Chain (CAS 96034-64-9): Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Meropenem Side Chain (CAS 96034-64-9)

A critical intermediate in carbapenem antibiotic synthesis, widely used in pharmaceutical manufacturing.

Key Parameters

Parameter Specification
Chemical Name (2S,4R)-2-[(1R)-1-Hydroxyethyl]-4-mercapto-1-pyrrolidinecarboxylic acid
CAS Number 96034-64-9
Molecular Formula C8H12N2O3S
Purity ≥99% (HPLC)
Storage 2-8°C in airtight container

Comparative Analysis

Feature Meropenem Side Chain Imipenem Side Chain
Stereochemical Complexity 3 chiral centers 2 chiral centers
Synthetic Yield 82-88% 75-80%
Stability 12 months 9 months

2. Key Applications & Uses

Pharmaceutical Manufacturing

Essential component in meropenem API production, requiring strict ICH Q7 compliance.

Research Applications

  • Antibiotic derivative development
  • Beta-lactamase stability studies
  • Structure-activity relationship (SAR) research

3. Usage Scenarios & Best Practices

Synthetic Protocol

Typical reaction conditions: 0-5°C in anhydrous DMF, pH maintained at 6.8-7.2.

Quality Control

Test Method Specification
Assay HPLC 98.0-102.0%
Related Substances ICH Guidelines ≤0.5%

4. Real-World Client Case Studies

Case 1: Aurobindo Pharma Ltd. (India)

Achieved 15% yield improvement in meropenem synthesis through optimized side chain purification.

Case 2: Huaxing Pharma (China)

Reduced production costs by 22% after switching to our GMP-grade side chain material.

Case 3: European Research Consortium

Developed novel carbapenem derivatives using our side chain for antibiotic resistance studies.

5. Technical Inquiry & Contact

For technical specifications, COA, or bulk pricing:

Email: info@vivalr.com
Tel: (86) 15866781826

Request free sample or discuss custom synthesis requirements with our chemistry team.

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