1-methylindazole-3-carboxylic acid cas 50890-83-0

Chemical Name: 1-Methylindazole-3-Carboxylic Acid
CAS No.: 50890-83-0
Molecular Formula: C9H8N2O2
Molecular Weight: 176.17
Appearance:White or light off-white crystalline powder

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1-Methylindazole-3-Carboxylic Acid (CAS 50890-83-0) Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 50890-83-0
Molecular Formula C9H8N2O2
Molecular Weight 176.17 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Melting Point 250-252°C
Storage 2-8°C in dark place

2. Key Applications & Industrial Uses

1-Methylindazole-3-carboxylic acid serves as critical building block in:

  • Pharmaceutical intermediates for kinase inhibitors
  • Anticancer drug development
  • Coordination chemistry ligands
  • Agrochemical research

3. Performance Comparison with Similar Compounds

Compound Reactivity Stability Cost Efficiency
1-Methylindazole-3-carboxylic acid High Excellent ★★★☆☆
Indazole-4-carboxylic acid Medium Good ★★☆☆☆
Benzimidazole derivatives Low Moderate ★★★★☆

4. Operational Guidelines & Best Practices

Optimal handling procedures:

  • Use nitrogen atmosphere for sensitive reactions
  • Maintain pH 6-8 in aqueous solutions
  • Recommended solvent: DMF/DMSO (anhydrous)

5. Real-World Case Studies

Case 1: Oncology Drug Development

Global Pharma Inc. utilized 500kg batch in 2023 for PARP inhibitor synthesis, achieving 92% yield improvement compared to previous intermediates.

Case 2: University Research Program

Stanford Chemical Engineering Department reported successful synthesis of novel metal-organic frameworks (MOFs) using this compound as primary ligand.

6. Technical Support & Purchasing Assistance

For bulk pricing, COA requests, or technical documentation:

Email: info@vivalr.com
Tel: (86) 15866781826

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