Hesperidin (CAS 520-26-3) Comprehensive User Guide 2025
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industry Uses
- 3. Usage Guidelines & Best Practices
- 4. Case Studies: Real-World Implementations
- 5. Competitive Parameter Analysis
- 6. Procurement Consultation & Contact
1. Product Overview & Specifications
| Parameter | Hesperidin (CAS 520-26-3) |
|---|---|
| Chemical Name | (2S)-5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one |
| Molecular Formula | C28H34O15 |
| Molecular Weight | 610.56 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | ≥90%, ≥95%, ≥98% (HPLC) |
| Solubility | Sparingly soluble in water, soluble in DMSO and alkaline solutions |
2. Key Applications & Industry Uses
Pharmaceutical Applications
- Venotonic agent for chronic venous insufficiency treatment
- Anti-inflammatory supplement for osteoarthritis management
- Key component in cardiovascular health formulations
Nutraceutical Uses
- Antioxidant formulations for cellular protection
- Bioflavonoid complexes in immune support products
- Synergistic ingredient with vitamin C supplements
3. Usage Guidelines & Best Practices
Formulation Considerations
| Application | Recommended Concentration | Synergistic Compounds |
|---|---|---|
| Dietary Supplements | 50-500 mg/day | Vitamin C, Quercetin, Rutin |
| Topical Creams | 0.5-2% w/w | Hyaluronic Acid, Retinol |
4. Case Studies: Real-World Implementations
Case Study 1: European Nutraceutical Brand
- Challenge: Develop antioxidant complex with enhanced bioavailability
- Solution: 98% Hesperidin + Phospholipid complex
- Result: 3.2x bioavailability improvement vs standard extract
Case Study 2: Japanese Cosmetic Manufacturer
- Challenge: Create anti-aging serum for mature skin
- Formulation: 1.5% Hesperidin + 0.3% Retinol
- Outcome: 37% reduction in wrinkle depth (12-week trial)
5. Competitive Parameter Analysis
| Feature | Hesperidin | Rutin | Quercetin |
|---|---|---|---|
| Bioavailability | 8-12% (standard), 35%* (enhanced) | 2-5% | 15-20% |
| ORAC Value (μmol TE/g) | 15,000 | 12,000 | 28,000 |
| Optimal pH Stability | 3.5-6.5 | 4.0-7.0 | 2.5-5.5 |
*With advanced delivery systems
6. Procurement Consultation & Contact
For technical specifications, formulation support, or bulk pricing:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Request complimentary samples or detailed COA:
| Package Size | Purity | Lead Time |
|---|---|---|
| 1kg | 98% | 3-5 business days |
| 25kg | 95% | 2 weeks |



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