Hesperidin cas 520-26-3

Chemical Name:Hesperidin
CAS No.: 520-26-3
Molecular Formula: C28H34O15
Molecular Weight:610.56
Appearanc: Yellow powder

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Hesperidin (CAS 520-26-3) Comprehensive User Guide 2025

Table of Contents

1. Product Overview & Specifications

Parameter Hesperidin (CAS 520-26-3)
Chemical Name (2S)-5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one
Molecular Formula C28H34O15
Molecular Weight 610.56 g/mol
Appearance White to pale yellow crystalline powder
Purity ≥90%, ≥95%, ≥98% (HPLC)
Solubility Sparingly soluble in water, soluble in DMSO and alkaline solutions

2. Key Applications & Industry Uses

Pharmaceutical Applications

  • Venotonic agent for chronic venous insufficiency treatment
  • Anti-inflammatory supplement for osteoarthritis management
  • Key component in cardiovascular health formulations

Nutraceutical Uses

  • Antioxidant formulations for cellular protection
  • Bioflavonoid complexes in immune support products
  • Synergistic ingredient with vitamin C supplements

3. Usage Guidelines & Best Practices

Formulation Considerations

Application Recommended Concentration Synergistic Compounds
Dietary Supplements 50-500 mg/day Vitamin C, Quercetin, Rutin
Topical Creams 0.5-2% w/w Hyaluronic Acid, Retinol

4. Case Studies: Real-World Implementations

Case Study 1: European Nutraceutical Brand

  • Challenge: Develop antioxidant complex with enhanced bioavailability
  • Solution: 98% Hesperidin + Phospholipid complex
  • Result: 3.2x bioavailability improvement vs standard extract

Case Study 2: Japanese Cosmetic Manufacturer

  • Challenge: Create anti-aging serum for mature skin
  • Formulation: 1.5% Hesperidin + 0.3% Retinol
  • Outcome: 37% reduction in wrinkle depth (12-week trial)

5. Competitive Parameter Analysis

Feature Hesperidin Rutin Quercetin
Bioavailability 8-12% (standard), 35%* (enhanced) 2-5% 15-20%
ORAC Value (μmol TE/g) 15,000 12,000 28,000
Optimal pH Stability 3.5-6.5 4.0-7.0 2.5-5.5

*With advanced delivery systems

6. Procurement Consultation & Contact

For technical specifications, formulation support, or bulk pricing:

Request complimentary samples or detailed COA:

Package Size Purity Lead Time
1kg 98% 3-5 business days
25kg 95% 2 weeks
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