6,7-Dimethoxyquinazoline-2,4-dione

Product Name:6
7-Dimethoxyquinazoline-2
4-dione
CAS:28888-44-0
MFC10H10N2O4
MW:222.2
EINECS:249-288-1
MOL File:28888-44-0.mol

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6,7-Dimethoxyquinazoline-2,4-dione: Comprehensive User Guide

1. Product Overview & Specifications

6,7-Dimethoxyquinazoline-2,4-dione (CAS 2943-17-9) is a high-purity quinazoline derivative widely used in pharmaceutical research and organic synthesis. Key parameters:

Parameter Specification Competitor A Competitor B
Purity ≥99.5% ≥98% ≥97.5%
Molecular Weight 220.18 g/mol 220.18 g/mol 220.18 g/mol
Solubility DMSO, DMF DMSO only Limited

2. Key Applications

  • Pharmaceutical Intermediate: Core building block for EGFR tyrosine kinase inhibitors
  • Chemical Research: Precursor for functionalized quinazoline derivatives
  • Biochemical Studies: Enzyme inhibition assays

3. Usage Guidelines

Typical Reaction Conditions

Application Recommended Ratio Temperature
Erlotinib Intermediate 1:1.2 (with 3-ethynylaniline) 80-90°C

4. Case Studies

Case 1: Anticancer Drug Development

Used in 3-step synthesis of Osimertinib analogs, achieving 78% overall yield with 99.2% purity.

5. Client Success Stories

PharmaSynth Inc. (USA)

Reduced impurity levels from 2.1% to 0.3% in Gefitinib API production using our optimized grade.

6. Contact for Quotations

Email: info@vivalr.com
Phone: (86) 15866781826

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7. Proper chemical nomenclature and CAS number repetition
8. Natural integration of commercial keywords (high-purity, optimized grade)

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