2-Bromo-5-methylthiophene: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2-Bromo-5-methylthiophene (CAS 5922-34-7) is a brominated thiophene derivative widely used in organic synthesis. Key specifications include:
| Parameter | 2-Bromo-5-methylthiophene | 2-Bromo-thiophene |
|---|---|---|
| Molecular Formula | C5H5BrS | C4H3BrS |
| Molecular Weight | 177.06 g/mol | 163.03 g/mol |
| Boiling Point | 185-187°C | 150-152°C |
Advantages: Enhanced solubility in organic solvents compared to non-methylated analogs, ideal for cross-coupling reactions.
2. Applications of 2-Bromo-5-methylthiophene
2.1 Pharmaceutical Intermediates
Used in Suzuki-Miyaura couplings to synthesize tyrosine kinase inhibitors and antiviral agents.
2.2 Organic Electronics
Key monomer for conductive polymers in OLEDs and organic transistors.
2.3 Agrochemical Synthesis
Building block for herbicides and fungicides with improved stability.
3. Usage Scenarios & Case Studies
3.1 Synthesis of Anticancer Drug Intermediate
Process: Reacted with boronic acid via Pd-catalyzed coupling to form biaryl structures (85% yield).
3.2 Conductive Polymer Production
Method: Electropolymerization with EDOT to create PEDOT analogs (conductivity: 120 S/cm).
4. Client Success Stories
4.1 PharmaTech Solutions (Germany)
Application: Synthesized dasatinib intermediates. Result: 20% faster reaction kinetics vs. 2-bromothiophene.
4.2 NanoMaterials Inc. (USA)
Application: Developed flexible OLED materials. Outcome: Achieved 15% higher luminous efficiency.
4.3 AgroChem Ltd. (India)
Application: Created next-gen fungicide. Result: 99% pathogen inhibition at 50 ppm concentration.
5. Contact for Inquiries
Request custom synthesis or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
ISO 9001-certified production | GC/HPLC purity reports available | Global shipping
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