1. Product Overview & Specifications

2. Key Applications & Chemical Properties

Primary Function: Selective oxidation of primary/secondary alcohols to aldehydes/ketones under anhydrous conditions.

Advantages Over Alternatives:

• Prevents over-oxidation to carboxylic acids
• Compatible with acid-sensitive substrates
• Controlled reaction kinetics in aprotic solvents

Industrial Applications:

• Pharmaceutical intermediates synthesis
• Fine chemical production (e.g., fragrances)
• Polymer precursor modification

3. Operational Guidelines & Reaction Mechanisms

Standard Reaction Protocol:

1. Prepare anhydrous CH₂Cl₂ environment
2. Add 1.1–7.0 equivalents PCC to substrate (1:1 molar ratio)
3. Maintain 0–25°C for 4–24 hours
4. Terminate reaction with diethyl ether
5. Filter through Celite® to remove chromium residues

Catalytic Enhancements:

• 3Å molecular sieves: Accelerate reaction rate by 30–50%
• Acetic acid buffer: Improve selectivity for allylic alcohols

4. Safety Protocols & Hazard Management

5. Verified Use Cases & Industry Applications

Case Study 1: Pharmaceutical Intermediate Synthesis

Client: Top 10 Global Pharma Company
Process: Conversion of 2,7-octadien-1-ol to corresponding aldehyde (92% yield)
Scale: 500 kg batch production

Case Study 2: Fragrance Manufacturing

Client: European Specialty Chemicals Producer
Application: Selective oxidation of citronellol to citronellal
Result: 98.5% purity achieved with <1% over-oxidation

6. Supplier Information & Custom Solutions

Request Custom Formulation:

Contact our technical team for bulk orders or specialized grades:
Email: info@vivalr.com
Tel: (86) 15866781826