2-Amino-3,5-dibromopyrazine

2-Amino-3,5-dibromopyrazine: Comprehensive Product Guide

Table of Contents

• Product Overview
• Specifications & Comparative Analysis
• Key Applications in Pharmaceutical & Chemical Industries
• Industry Case Studies
• Handling & Safety Guidelines
• Contact for Customized Solutions

Product Overview

2-Amino-3,5-dibromopyrazine (CAS 102614-18-4) is a brominated heterocyclic compound widely used as a versatile intermediate in organic synthesis. Its molecular formula is C₄H₃Br₂N₃, with a molecular weight of 280.90 g/mol. This off-white crystalline powder is highly soluble in DMF and THF, with a typical purity of ≥97% (HPLC).

Specifications & Comparative Analysis

Key Applications

Pharmaceutical Intermediate

Used in synthesizing kinase inhibitors (e.g., Bruton’s tyrosine kinase inhibitors) through Suzuki-Miyaura cross-coupling reactions.

Agrochemical Development

Critical component in creating novel fungicides with enhanced bioavailability and environmental stability.

OLED Materials

Serves as electron-deficient building blocks for thermally activated delayed fluorescence (TADF) emitters.

Industry Case Studies

Case 1: Antiviral Drug Development

Client: European Pharma Research Group
Challenge: Required high-purity brominated intermediates for RNA virus inhibitor synthesis
Solution: Supplied 5kg batches with 99.3% purity under ISO Class 7 cleanroom conditions
Result: Achieved 92% yield in key coupling reaction (vs. 78% with previous supplier)

Case 2: Organic Semiconductor Research

Client: US Materials Science Institute
Challenge: Needed consistent bromine positioning for π-conjugated polymer synthesis
Solution: Custom synthesis with regiospecificity >99.5%
Result: Developed polymers with 15% improved charge mobility

Safety & Handling

Request Customized Solutions

Our technical team specializes in:

• Bulk synthesis (up to 100kg/month capacity)
• Isotope-labeled derivatives (e.g., ¹³C, ¹⁵N)
• Regioselective bromination services

Contact our experts for technical specifications or custom synthesis projects:
Email: info@vivalr.com
Tel: (86) 15866781826