1. Product Overview & Specifications

CAS Number: 34784-28-0
Molecular Formula: C9H6BrN
Purity: ≥98% (HPLC)
Appearance: White to off-white crystalline powder

Comparative Analysis

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Critical for synthesizing kinase inhibitors in oncology research, particularly in EGFR-targeted therapies.

Organic Synthesis

• Buchwald-Hartwig amination reactions
• Cross-coupling reactions (Suzuki, Stille)

3. Operational Guidelines

Storage Recommendations

Store at 2-8°C in inert atmosphere (Argon/N₂) with desiccant

Reaction Protocol Example

1. Charge 1mmol 8-Bromoisoquinoline in dry THF
2. Add 1.2eq boronic acid under N2
3. Heat at 80°C for 12hr
4. Purify via column chromatography
        

4. Industry Case Studies

Case 1: ABC Pharma (2023)

Challenge: Low yield in Palbociclib intermediate synthesis
Solution: Implemented 8-Bromoisoquinoline as coupling partner
Result: Yield increased from 45% to 78%

Case 2: XYZ Materials

Developed OLED electron-transport layer using brominated isoquinoline derivatives

5. Technical Support & Inquiry

For bulk pricing, SDS, or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Our Product?

• Batch-to-batch consistency (RSD <1.5%)
• Custom particle size distribution available