8-Aminoquinaldine

Product Name:8-Aminoquinaldine
CAS:18978-78-4
MFC10H10N2
MW:158.2
EINECS:606-190-7
MOL File:18978-78-4.mol

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8-Aminoquinaldine Comprehensive User Guide

1. Product Overview & Specifications

Chemical Identification

IUPAC Name: 2-Methylquinolin-8-amine

CAS No.: 18978-78-4

Molecular Formula: C10H10N2

Molecular Weight: 158.2 g/mol

Appearance: Yellow to light brown crystalline powder

Physical Properties

Property Value
Melting Point 56–58°C
Boiling Point 316.6°C (at 760 mmHg)
Density 1.2 g/cm³
Solubility Sparingly soluble in water; soluble in organic solvents

2. Key Applications

Pharmaceutical Intermediates

Used in synthesis of antimalarial agents and chemotherapeutic compounds due to its quinoline backbone.

Agrochemical Production

Serves as a precursor for crop protection agents targeting fungal and bacterial pathogens.

Organic Dyes & Materials

Acts as a chromophore in dye manufacturing and coordination chemistry for metal-organic frameworks (MOFs).

3. Operational Guidelines

Storage Recommendations

  • Store in airtight containers at 2–8°C.
  • Protect from light and moisture.

Handling Precautions

  • Use PPE: Nitrile gloves, chemical goggles, and lab coats.
  • Operate under fume hoods to minimize inhalation exposure.

4. Safety & Handling

Hazard Classification

  • H302: Harmful if swallowed.
  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.

Emergency Measures

Spill Response: Absorb with inert material and dispose as hazardous waste.

Firefighting: Use CO2, dry chemical, or foam. Avoid water spray.

5. Industry Case Studies

Case Study 1: Pharmaceutical Synthesis

Client: A European API manufacturer

Application: Integrated 8-Aminoquinaldine into a novel antimalarial drug intermediate, achieving 98% purity in scaled production.

Case Study 2: Specialty Dyes

Client: A Japanese chemical company

Application: Developed high-stability textile dyes using 8-Aminoquinaldine as a key ligand, enhancing colorfastness by 40%.

6. Contact for Technical & Commercial Inquiries

Email: info@vivalr.com

Phone: (86) 15866781826

Request bulk pricing, SDS, or custom synthesis options.

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