(R)-(-)-3-Pyrrolidinol Hydrochloride: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
(R)-(-)-3-Pyrrolidinol Hydrochloride (CAS 69441-04-7) is a chiral building block widely used in asymmetric synthesis. Key parameters:
| Parameter | Specification | (S)-(+)-Isomer | Racemic Mixture |
|---|---|---|---|
| Molecular Formula | C4H9NO·HCl | Same | Same |
| Optical Purity | ≥98% ee | ≥98% ee | N/A |
| Storage | 2-8°C | 2-8°C | Room Temp |
2. Key Applications
2.1 Pharmaceutical Intermediates
Used in synthesizing chiral amines for antidepressants and antivirals like Abacavir.
2.2 Asymmetric Catalysis
Essential for creating P,N-ligands in transition-metal catalyzed reactions.
3. Usage Scenarios
3.1 Antidepressant Synthesis
Used in 5-step synthesis of Vilazodone (Viibryd®), achieving 92% enantiomeric excess.
4. Customer Case Studies
4.1 PharmaGen Solutions
Reduced byproduct formation by 40% in Rolapitant intermediate synthesis using our (R)-isomer.
4.2 ChemTech Ltd
Achieved 99% yield in Buchwald-Hartwig amination using our product as chiral modifier.
5. Request Quotation
Contact our technical team for batch-specific COA and pricing:
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