Propylene Glycol Diethylhexanoate CAS 93981-97-6

Chemical Name: Propylene Glycol Diethylhexanoate
Synonyms: 1-methylethylene 2-ethylhexanoate
CAS No.: 93981-97-6
Molecular Formula: C19H36O4
Molecular Weight: 328.49
Appearance: Liquid

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Propylene Glycol Diethylhexanoate CAS 93981-97-6: Comprehensive Guide & Industry Applications (2025)

Table of Contents

1. Product Overview & Specifications

Parameter Specification
Chemical Name Propylene Glycol Diethylhexanoate
CAS Number 93981-97-6
Molecular Formula C16H30O4
Molecular Weight 286.41 g/mol
Appearance Clear colorless liquid
Solubility Miscible with oils, ethanol; insoluble in water
Density (25°C) 0.91-0.93 g/cm³
Boiling Point >200°C
Flash Point >150°C
Primary Applications Cosmetics, Pharmaceuticals, Lubricants, Plasticizers

2. Key Applications & Functional Advantages

2.1 Cosmetic Formulations

As premium emollient with non-greasy texture:

  • Enhances SPF product spreadability (UV filter compatibility)
  • Improves moisturizer longevity on skin
  • Reduces stickiness in hair care products

2.2 Pharmaceutical Uses

  • Solubilizer for topical drug delivery systems
  • Stabilizer for ointments/creams (pH 4-8 stable)
  • Penetration enhancer for transdermal patches

2.3 Industrial Applications

  • High-temperature lubricant additive
  • Plasticizer for specialty polymers
  • Metalworking fluid component

3. Performance Comparison With Alternatives

Parameter PG Diethylhexanoate PG Monocaprylate PG Dicaprylate/Dicaprate
Viscosity (25°C) 12-15 mPa·s 20-25 mPa·s 18-22 mPa·s
Oxidative Stability Excellent Good Moderate
Cold Resistance -40°C stable -20°C stable -30°C stable
SPF Synergy High Medium Low
FDA Approval Status GRAS/EAFUS listed Limited approval Not approved

4. Industrial Use Cases & Formulation Examples

4.1 Cosmetic Application: Long-lasting Moisturizer

Formula %:

  • 5% PG Diethylhexanoate
  • 8% Caprylic/Capric Triglyceride
  • 3% Vitamin E Acetate
  • 2% Hyaluronic Acid

Benefits: 24-hour hydration without oiliness

4.2 Pharmaceutical Use: Transdermal Analgesic Patch

  • 15% Active ingredient
  • 10% PG Diethylhexanoate (penetration enhancer)
  • Polyacrylate adhesive matrix

Result: 40% faster drug absorption vs standard formulations

5. Verified Client Success Stories

5.1 Skincare Innovations Ltd. (UK)

  • Challenge: Reformulate SPF50+ cream reducing white cast
  • Solution: 7% PG Diethylhexanoate as primary emollient
  • Outcome: 30% reduction in titanium dioxide content while maintaining SPF

5.2 PharmaHealth Solutions (USA)

  • Requirement: Stabilize pH-sensitive topical antibiotic
  • Implementation: 12% PG Diethylhexanoate in ointment base
  • Result: 18-month shelf life extension at 25°C

6. Technical Support & Customized Solutions

Contact our chemical engineers for application-specific guidance:

Email: info@vivalr.com
Tel: (86) 15866781826

Request:

  • Free technical datasheet (SDS/TDS)
  • Customized formulation samples
  • Regulatory compliance consultation
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