4-Bromopyridin-2-ol: Product Guide & Industry Insights
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Functional Uses
- 3. Operational Guidelines & Best Practices
- 4. Industry Use Cases
- 5. Client Success Stories
- 6. Request Customized Solutions
1. Product Specifications & Comparative Analysis
| Parameter | 4-Bromopyridin-2-ol | 2-Bromopyridine | 2-Hydroxypyridine |
|---|---|---|---|
| CAS Number | 42286-28-6 | 109-04-6 | 142-08-5 |
| Molecular Formula | C5H4BrNO | C5H4BrN | C5H5NO |
| Purity Grade | ≥98% (HPLC) | ≥95% | ≥97% |
| Primary Applications | Pharmaceutical intermediates, Catalytic ligands | Organic synthesis | Metal chelation |
2. Key Applications & Functional Uses
Pharmaceutical Manufacturing
Critical intermediate in synthesizing antiviral agents and kinase inhibitors, with enhanced reactivity at the ortho position compared to pyridine derivatives.
Agrochemical Production
Enables development of advanced crop protection chemicals through bromine-mediated coupling reactions.
Materials Science
Facilitates creation of conductive polymers and metal-organic frameworks (MOFs) via its dual functional groups.
3. Operational Guidelines & Best Practices
Handling Protocol
- Store in inert atmosphere (N2) at 2-8°C
- Use dry DMF as preferred solvent for Buchwald-Hartwig couplings
- Maintain pH 6-8 in aqueous reactions
4. Industry Use Cases
Case 1: Antiviral Drug Synthesis
Used in 7-step synthesis of Brincidofovir analogs, achieving 82% yield improvement over traditional methods.
Case 2: Catalytic Cross-Coupling
Enabled Suzuki-Miyaura reactions with turnover numbers (TON) exceeding 105 in palladium-based systems.
5. Client Success Stories
PharmaHealth Inc. (2023)
Reduced production costs by 38% in kinase inhibitor manufacturing through optimized bromopyridinol-mediated pathways.
AgroSolutions Ltd. (2024)
Developed next-generation fungicide using our 4-Bromopyridin-2-ol, achieving 99.2% purity in final API.
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ orders)
- Custom synthesis protocols
- Regulatory documentation support
Email: info@vivalr.com
Phone: (86) 15866781826


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