2-Hydroxy-3-cyanopyridine

Product Name:2-Hydroxy-3-cyanopyridine
CAS:20577-27-9
MFC6H4N2O
MW:120.11
EINECS:
MOL File:20577-27-9.mol

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2-Hydroxy-3-cyanopyridine: Comprehensive Guide for Industrial & Research Applications

Contents

1. Technical Parameters & Market Comparison

Parameter Standard Grade Pharma Grade Research Grade
Purity ≥98% ≥99.5% ≥99.9%
CAS Number 5310-88-9
Molecular Formula C6H4N2O
Thermal Stability 180°C 185°C 190°C

2. Industrial Utilization Scenarios

Pharmaceutical Intermediates

Critical precursor for:

  • Kinase inhibitor APIs
  • Antiviral drug candidates
  • Neurological disorder treatments

Agrochemical Formulations

Key component in:

  • Systemic herbicides (pH-dependent activation)
  • Fungicide stabilizers
  • Neonicotinoid alternatives

3. Handling Protocol

  1. Storage: Maintain in nitrogen atmosphere at 2-8°C
  2. Reaction Compatibility: Compatible with Pd-catalyzed couplings
  3. Safety: Use glove boxes for moisture-sensitive applications

4. Documented Applications

Case 1: Anticancer Drug Development

European pharma company achieved 92% yield improvement in Bruton’s tyrosine kinase inhibitor synthesis through optimized cyano group activation.

Case 2: Next-Gen Herbicides

US agrochemical manufacturer developed pH-responsive herbicide showing 40% increased field persistence compared to traditional formulations.

5. Verified Client Experiences

Client Application Result
Shanghai PharmaTech JAK2 inhibitor intermediate Reduced synthesis steps from 7 to 4
Bayer CropScience Soil-stable fungicide Extended protection duration by 3 weeks

6. Technical & Procurement Support

For batch-specific analysis reports or custom synthesis requirements:

Related Chemical Services

Explore our custom heterocyclic compound synthesis capabilities or review PubChem safety data for regulatory compliance guidance.

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