4-Chloro-2-methylthiopyrimidine: Comprehensive Guide for Researchers & Industry Professionals
Table of Contents
- Product Overview
- Technical Specifications & Comparative Analysis
- Industrial Applications
- Usage Guidelines
- Industry Case Studies
- Contact for Technical Consultation
Product Overview
4-Chloro-2-methylthiopyrimidine (CAS 36230-15-4) is a specialized heterocyclic compound with molecular formula C5H5ClN2S. This pyrimidine derivative features:
- Molecular weight: 160.62 g/mol
- Appearance: White to off-white crystalline powder
- Purity: ≥98% (HPLC)
- Storage: 2-8°C in airtight container
Technical Specifications
| Parameter | 4-Chloro-2-methylthiopyrimidine | Similar Compound A | Similar Compound B |
|---|---|---|---|
| Reactivity | High (Cl substitution) | Moderate | Low |
| Thermal Stability | Stable up to 150°C | 120°C | 100°C |
| Solubility | DCM, THF, DMF | Limited | Water-miscible |
Industrial Applications
Key utilization in:
- Pharmaceutical intermediates (HIV protease inhibitors)
- Agrochemical precursors (systemic fungicides)
- Organic electronics (semiconductor dopants)
Recommended Protocols
Nucleophilic Substitution Example:
- Prepare 1M solution in anhydrous DMF
- Add 1.2eq amine nucleophile
- Heat at 80°C for 6-8 hours under N2
Industry Implementations
Case 1: Antiviral Drug Development
Client: European Pharma Co., Ltd. (2023)
Application: Key intermediate in protease inhibitor synthesis
Outcome: 92% yield improvement vs previous synthesis route
Case 2: Crop Protection Formulation
Client: Asia AgroChem Group (2024)
Application: Fungicidal metabolite precursor
Outcome: 40% cost reduction in production scale-up
Technical & Commercial Consultation
For batch-specific COA, custom synthesis, or bulk pricing:
- Email: info@vivalr.com
- Tel: (86) 15866781826


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