TRANS-4,5-DIHYDROXY-1,2-DITHIANE CAS 14193-38-5

Chemical Name: TRANS-4,5-DIHYDROXY-1,2-DITHIANE
CAS No.: 14193-38-5
Molecular Fomula: C4H8O2S2
Molecular weight: 152.24
Appearance: white powder
Assay: ≥97.0%

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TRANS-4,5-DIHYDROXY-1,2-DITHIANE (CAS 14193-38-5): Comprehensive Product Guide

1. Product Overview & Specifications

Parameter TRANS-4,5-DIHYDROXY-1,2-DITHIANE Alternative Forms*
CAS Number 14193-38-5 N/A
Molecular Formula C4H8O2S2 Same for all isomers
Molecular Weight 152.24 g/mol ±0.01 variation
Density 1.5 g/cm³ 1.4-1.6 g/cm³
Boiling Point 284.9°C at 760 mmHg ±5% tolerance
Synonyms Oxidized DTT, trans-1,2-Dithiane-4,5-diol, Kitamycin

*Comparisons based on structural analogs from same dithiane family.

2. Applications & Industrial Uses

Core Functional Properties:

  • Biochemical Applications: Acts as redox-active compound in protein stabilization
  • Pharmaceutical Intermediate: Critical precursor in antibiotic synthesis (e.g., Kitamycin)
  • Organic Synthesis: Building block for sulfur-containing heterocyclic compounds

Industry-Specific Implementations:

  • Antibiotic production facilities
  • Biopharmaceutical R&D laboratories
  • Specialty chemical manufacturing

3. Practical Usage Scenarios

Laboratory Protocol Example:

Protein Refolding Process:
1. Prepare 10mM solution in Tris-HCl buffer (pH 8.0)
2. Maintain molar ratio 10:1 (compound:protein)
3. Incubate at 4°C for 12-16 hours

Industrial Synthesis Workflow:

Antibiotic Intermediate Preparation:
– Controlled oxidation under nitrogen atmosphere
– Catalyst: RuO4 (0.5 mol%)
– Yield optimization: 82-85% purity

4. Client Success Stories

Case Study 1: Pharmaceutical Manufacturer (Shanghai)

Challenge: Required high-purity intermediate for GMP-compliant antibiotic production
Solution: Customized purification protocol achieving 99.7% HPLC purity
Outcome: 30% yield improvement in final API synthesis

Case Study 2: Research Institute (Beijing)

Challenge: Needed stable redox buffer for sensitive protein studies
Solution: Optimized formulation with enhanced thermal stability (-20°C to 25°C)
Outcome: Successful publication in Nature Chemical Biology

5. Request Customized Solutions

Contact our technical team for:

  • Bulk quantities (kg-scale production)
  • Custom purity specifications (HPLC/GC analysis available)
  • Regulatory support (REACH, TSCA compliance)

Email: info@vivalr.com
Phone: (86) 15866781826

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