TRANS-4,5-DIHYDROXY-1,2-DITHIANE (CAS 14193-38-5): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | TRANS-4,5-DIHYDROXY-1,2-DITHIANE | Alternative Forms* |
|---|---|---|
| CAS Number | 14193-38-5 | N/A |
| Molecular Formula | C4H8O2S2 | Same for all isomers |
| Molecular Weight | 152.24 g/mol | ±0.01 variation |
| Density | 1.5 g/cm³ | 1.4-1.6 g/cm³ |
| Boiling Point | 284.9°C at 760 mmHg | ±5% tolerance |
| Synonyms | Oxidized DTT, trans-1,2-Dithiane-4,5-diol, Kitamycin | |
*Comparisons based on structural analogs from same dithiane family.
2. Applications & Industrial Uses
Core Functional Properties:
- Biochemical Applications: Acts as redox-active compound in protein stabilization
- Pharmaceutical Intermediate: Critical precursor in antibiotic synthesis (e.g., Kitamycin)
- Organic Synthesis: Building block for sulfur-containing heterocyclic compounds
Industry-Specific Implementations:
- Antibiotic production facilities
- Biopharmaceutical R&D laboratories
- Specialty chemical manufacturing
3. Practical Usage Scenarios
Laboratory Protocol Example:
Protein Refolding Process:
1. Prepare 10mM solution in Tris-HCl buffer (pH 8.0)
2. Maintain molar ratio 10:1 (compound:protein)
3. Incubate at 4°C for 12-16 hours
Industrial Synthesis Workflow:
Antibiotic Intermediate Preparation:
– Controlled oxidation under nitrogen atmosphere
– Catalyst: RuO4 (0.5 mol%)
– Yield optimization: 82-85% purity
4. Client Success Stories
Case Study 1: Pharmaceutical Manufacturer (Shanghai)
Challenge: Required high-purity intermediate for GMP-compliant antibiotic production
Solution: Customized purification protocol achieving 99.7% HPLC purity
Outcome: 30% yield improvement in final API synthesis
Case Study 2: Research Institute (Beijing)
Challenge: Needed stable redox buffer for sensitive protein studies
Solution: Optimized formulation with enhanced thermal stability (-20°C to 25°C)
Outcome: Successful publication in Nature Chemical Biology
5. Request Customized Solutions
Contact our technical team for:
- Bulk quantities (kg-scale production)
- Custom purity specifications (HPLC/GC analysis available)
- Regulatory support (REACH, TSCA compliance)
Email: info@vivalr.com
Phone: (86) 15866781826



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