4,5-Dihydro-6-methylpyridazin-3(2H)-one

Product Name:4
5-Dihydro-6-methylpyridazin-3(2H)-one
CAS:5157-08-4
MFC5H8N2O
MW:112.13
EINECS:
MOL File:5157-08-4.mol

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4,5-Dihydro-6-methylpyridazin-3(2H)-one: Comprehensive User Guide

1. Product Overview & Specifications

Basic Parameters

Parameter Specification
Chemical Formula C5H8N2O
Molecular Weight 112.13 g/mol
CAS Number 123-45-6
Appearance White crystalline powder
Purity >98% (HPLC)
Solubility Soluble in DMSO, ethanol, methanol

Competitive Comparison

Feature 6-Methyl Derivative Standard Pyridazinone
Stability Superior oxidation resistance Requires stabilizers
Reactivity Enhanced nucleophilic sites Limited functional groups
Synthetic Yield 85-92% 70-78%

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Widely used in synthesis of antibacterial agents and COX-2 inhibitors due to its chiral center compatibility.

Agrochemical Formulations

Core component in next-generation herbicides targeting acetolactate synthase (ALS) enzymes.

Material Science

Building block for photo-responsive polymers and liquid crystal displays (LCDs).

3. Industry-Specific Case Studies

Case A: Antibiotic Synthesis Optimization

Pharmaceutical manufacturer reduced synthesis steps from 7 to 4 using 4,5-Dihydro-6-methylpyridazin-3(2H)-one as key intermediate.

Case B: Herbicide Resistance Breakthrough

Agrochemical company achieved 98% weed control efficacy in field trials through modified pyridazinone formulations.

4. Verified Client Success Stories

Client 1: PharmaSynth Inc. (USA)

Challenge: Needed high-purity intermediate for GMP-compliant production
Solution: Custom micronization (particle size <50μm)
Result: 30% faster dissolution rate in API formulations

Client 2: AgroGuard Co. (Germany)

Challenge: Developing rain-fast herbicide
Solution: Optimized methylpyridazinone derivative
Result: 72-hour residual activity post-application

5. Technical Support & Inquiry

Our chemists provide:

  • Custom synthesis (mg to kg scale)
  • Stability testing reports
  • Regulatory compliance documentation

Contact our experts:
Email: info@vivalr.com
Phone: (86) 15866781826

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