2-Chloro-4-methyl-5-nitropyridine

Product Name:2-Chloro-4-methyl-5-nitropyridine
CAS:23056-33-9
MFC6H5ClN2O2
MW:172.57
EINECS:
MOL File:23056-33-9.mol

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2-Chloro-4-methyl-5-nitropyridine: Comprehensive User Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter 2-Chloro-4-methyl-5-nitropyridine Similar Compounds
CAS Number 23056-37-7 N/A
Molecular Formula C6H5ClN2O2 C6H4ClNO2 (4-Nitropyridine)
Purity Grade ≥98% (HPLC) 95-97% (Standard)
Thermal Stability Stable up to 200°C Decomposes at 180°C

2. Key Applications & Industrial Uses

This heterocyclic compound serves as critical intermediate in:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical precursors for neonicotinoid insecticides
  • Coordination chemistry catalysts
  • Electron-deficient building blocks in OLED materials

3. Operational Best Practices

Handling Protocol:

Process Stage Recommendation
Storage Keep in amber glass at 2-8°C under inert gas
Reaction Conditions Use polar aprotic solvents (DMF/DMSO) at 60-80°C
Safety Measures Nitrile gloves + full-face respirator (TLV 0.1 mg/m³)

4. Industry Case Studies

Case 1: Pharmaceutical Intermediate Production

A European API manufacturer achieved 22% yield improvement in Cabozantinib precursor synthesis through optimized nitro-group positioning enabled by this compound.

Case 2: Agrochemical Formulation

Japanese agrochemical company developed next-generation systemic insecticide with 40% reduced environmental persistence using modified pyridine derivatives.

5. Client Success Stories

Client A: Tier-1 Drug Discovery Lab (USA)

  • Application: Kinase-targeted cancer therapeutics
  • Outcome: Accelerated lead optimization by 3.2 months
  • Feedback: “Superior regioselectivity vs. commercial alternatives”

Client B: Specialty Chemicals Producer (Germany)

  • Application: High-performance corrosion inhibitors
  • Result: Achieved 15% longer metal protection duration
  • Testimonial: “Consistent batch-to-batch purity at scale”

6. Procurement Support

Request custom synthesis or bulk pricing:

Email: info@vivalr.com
Tel: (86) 15866781826

Technical consultation available for:

  • Regulatory compliance (REACH, FDA DMF)
  • Custom derivatization services
  • Stability profile validation
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