Product Name:N-Methylpyrrole-2-carboxylic acid
CAS:6973-60-0
MFC6H7NO2
MW:125.13
EINECS:230-217-8
MOL File:6973-60-0.mol
Parameter | Specification |
---|---|
CAS Number | 1193-69-7 |
Molecular Formula | C6H7NO2 |
Purity | ≥98% (HPLC) |
Melting Point | 128-132°C |
Storage Conditions | 2-8°C in airtight container |
Pharmaceutical Intermediate: Critical component in synthesis of kinase inhibitors and antipsychotic drugs.
Electrochemical Materials: Building block for conductive polymers in organic electronics.
Agrochemicals: Precursor for novel pesticide formulations with improved stability.
Property | N-Methylpyrrole-2-CA | Pyrrole-2-Carboxylic Acid |
---|---|---|
Solubility in DMF | Excellent | Moderate |
Thermal Stability | Up to 250°C | Up to 200°C |
Handling Precautions: Use nitrogen atmosphere for sensitive reactions requiring anhydrous conditions.
Optimized Reaction Conditions: 0.1-0.3 molar equivalents typically used in palladium-catalyzed cross-couplings.
Case 1: Leading European Pharma Co. achieved 23% yield improvement in Lorlatinib intermediate synthesis through optimized methylation protocols.
Case 2: US Electronics Manufacturer developed flexible OLED components with enhanced conductivity using polymer derivatives.
Case 3: Asian Agrochemical Producer created weather-resistant fungicide with 18-month shelf life stability.
Selection Criteria | Best Practice |
---|---|
Purity Verification | Require batch-specific HPLC reports |
Regulatory Compliance | Confirm REACH/USP/EP certifications |
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