N-Methylpyrrole-2-carboxylic acid

Product Name:N-Methylpyrrole-2-carboxylic acid
CAS:6973-60-0
MFC6H7NO2
MW:125.13
EINECS:230-217-8
MOL File:6973-60-0.mol

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N-Methylpyrrole-2-carboxylic Acid: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 1193-69-7
Molecular Formula C6H7NO2
Purity ≥98% (HPLC)
Melting Point 128-132°C
Storage Conditions 2-8°C in airtight container

2. Key Applications

Pharmaceutical Intermediate: Critical component in synthesis of kinase inhibitors and antipsychotic drugs.

Electrochemical Materials: Building block for conductive polymers in organic electronics.

Agrochemicals: Precursor for novel pesticide formulations with improved stability.

3. Comparative Analysis

Property N-Methylpyrrole-2-CA Pyrrole-2-Carboxylic Acid
Solubility in DMF Excellent Moderate
Thermal Stability Up to 250°C Up to 200°C

4. Usage Guidelines

Handling Precautions: Use nitrogen atmosphere for sensitive reactions requiring anhydrous conditions.

Optimized Reaction Conditions: 0.1-0.3 molar equivalents typically used in palladium-catalyzed cross-couplings.

5. Industry Case Studies

Case 1: Leading European Pharma Co. achieved 23% yield improvement in Lorlatinib intermediate synthesis through optimized methylation protocols.

Case 2: US Electronics Manufacturer developed flexible OLED components with enhanced conductivity using polymer derivatives.

Case 3: Asian Agrochemical Producer created weather-resistant fungicide with 18-month shelf life stability.

6. Procurement Recommendations

Selection Criteria Best Practice
Purity Verification Require batch-specific HPLC reports
Regulatory Compliance Confirm REACH/USP/EP certifications

7. Contact Our Experts

Email: info@vivalr.com
Phone: (86) 15866781826

Request custom synthesis scale-up plans or technical documentation:

  • GMP-grade production capabilities
  • Bulk quantity discounts (100kg+ orders)
  • Regulatory support packages
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