2-FLUORO-3-METHYLPYRIDINE-5-BORONIC ACID

Comprehensive Guide to 2-Fluoro-3-Methylpyridine-5-Boronic Acid

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Industry Uses
• 3. Performance Comparison with Similar Boronic Acids
• 4. Usage Guidelines & Best Practices
• 5. Real-World Case Studies
• 6. Technical Inquiry & Ordering

1. Product Overview & Specifications

2. Key Applications & Industry Uses

Pharmaceutical Intermediates

Critical building block for kinase inhibitors and oncology drugs via Suzuki-Miyaura cross-coupling reactions.

Agrochemical Development

Used in synthesis of advanced fungicides with improved metabolic stability due to fluorine substitution.

Material Science

Key component in organic electronic materials for OLED charge transport layers.

3. Performance Comparison

4. Usage Guidelines

Handling Protocol

Always maintain under nitrogen atmosphere during weighing and reaction charging.

Reaction Optimization

For Suzuki couplings: Use 1.1 eq boronic acid with Pd(PPh₃)₄ (0.8 mol%) in degassed THF/H₂O (3:1) at 80°C.

5. Real-World Case Studies

Case 1: Oncology Drug Development

Client: Top 10 Global Pharma Company
Application: Synthesized third-generation BTK inhibitor (Phase III trial)
Result: Achieved 94% yield in key coupling step, reduced catalyst cost by 40% vs previous routes

Case 2: OLED Material Innovation

Client: Leading Display Manufacturer
Application: Developed electron-transport layer with 18% efficiency improvement
Result: Enabled commercial production of blue OLED with 50,000hr lifespan

6. Technical Inquiry & Ordering

Request product samples or technical documents:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us?

• Batch-to-batch consistency (RSD <0.8%)
• Custom synthesis capabilities (mg to kg scale)
• Regulatory support (DMF, CMC documentation)