Comprehensive Guide to 3-Bromo-2-pyridinamine
Table of Contents
- 1. Product Overview & Specifications
- 2. Applications of 3-Bromo-2-pyridinamine
- 3. Usage Guidelines
- 4. Case Studies
- 5. Customer Success Stories
- 6. Request a Quote
1. Product Overview & Specifications
3-Bromo-2-pyridinamine (CAS 39856-55-2) is a brominated pyridine derivative widely used in pharmaceutical and chemical synthesis. Key parameters:
| Parameter | Value |
|---|---|
| Molecular Formula | C5H5BrN2 |
| Molecular Weight | 173.01 g/mol |
| Appearance | Off-white to light yellow crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in airtight container |
Comparative Analysis
| Feature | 3-Bromo-2-pyridinamine | 2-Bromo-3-pyridinamine |
|---|---|---|
| Reactivity | Higher in Suzuki couplings | Moderate |
| Stability | Stable under inert atmosphere | Light-sensitive |
2. Applications of 3-Bromo-2-pyridinamine
Pharmaceutical Intermediates
Used in synthesis of kinase inhibitors and antiviral agents.
Organic Synthesis
- Cross-coupling reactions (e.g., Buchwald-Hartwig amination)
- Building block for heterocyclic compounds
3. Usage Guidelines
Handling Precautions
Use in well-ventilated areas with PPE (gloves, goggles).
Reaction Optimization
Recommended conditions for coupling reactions:
- Catalyst: Pd(dppf)Cl2
- Temperature: 80-100°C
- Solvent: DMF/THF mixture
4. Case Studies
Case 1: Anticancer Drug Development
Used in 7-step synthesis of a tyrosine kinase inhibitor, achieving 82% yield in key amination step.
Case 2: Material Science Research
Modified into luminescent coordination polymers for OLED applications.
5. Customer Success Stories
PharmaTech Inc. (USA)
- Application: Hepatitis C protease inhibitor intermediate
- Result: Reduced synthesis steps from 5 to 3
- Feedback: “Consistent quality accelerated our preclinical trials”
EuroChem Research (Germany)
- Application: PET tracer precursor
- Result: Achieved 94% radiochemical purity
- Feedback: “Critical for our diagnostic platform development”
6. Request a Quote
Contact our technical team for bulk pricing and custom synthesis:
- Email: info@vivalr.com
- Phone: (86) 15866781826


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