2-{[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl]methylthio}-1H-benzimidazole

Product Name:2-{[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl]methylthio}-1H-benzimidazole
CAS:117977-21-6
MFC18H21N3O2S
MW:343.44
EINECS:601-502-8
MOL File:117977-21-6.mol

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1. Product Information & Specifications

Chemical Profile

Parameter Specification
IUPAC Name 2-{[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl]methylthio}-1H-benzimidazole
CAS Number [To be confirmed based on latest registry]
Molecular Formula C20H23N3O2S
Molecular Weight 369.48 g/mol

Comparative Analysis

Feature Our Compound Standard Alternatives
Water Solubility 0.5 mg/mL (25°C) 0.2-0.3 mg/mL
Thermal Stability Stable up to 150°C Decomposes at 120-130°C

2. Key Applications

Pharmaceutical Development

  • Proton pump inhibitor intermediate
  • Kinase inhibitor precursor

Biochemical Research

  • Cell signaling pathway studies
  • Enzyme inhibition assays

3. Usage Guidelines

Recommended Protocols

  1. Storage: -20°C under inert atmosphere
  2. Reconstitution: Use anhydrous DMSO
  3. Working concentration: 10-100 μM

4. Application Case Studies

Case 1: Gastroprotective Agent Development

Shanghai PharmaTech achieved 40% improvement in bioavailability through optimized synthesis routes using this compound as core intermediate.

Case 2: Oncology Research Breakthrough

University of Heidelberg researchers utilized the compound as tyrosine kinase inhibitor scaffold in NSCLC treatment studies.

5. Verified Client Implementations

Client A: Top 10 Global Pharma Company

  • Application: Large-scale API production
  • Annual consumption: 850kg
  • Purity requirement: >99.7%

Client B: EU Research Consortium

  • Application: Antimicrobial resistance studies
  • Project duration: 2022-2024
  • Results: 3 published papers

6. Request Customized Solutions

Contact our technical team for batch-specific COA or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

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