1. Product Overview & Specifications

2,6-Dichloro-1-fluoropyridinium triflate (CAS 220141-71-7) is a high-performance fluorination reagent widely used in organic synthesis. Key parameters:

2. Key Applications & Use Cases

2.1 Fluorination Reactions

Enables efficient nucleophilic fluorination in:

• Pharmaceutical intermediates (e.g., PET radiotracers)
• Agrochemical synthesis
• Electronic material precursors

2.2 Reaction Optimization

Typical reaction conditions:

Substrate (1 eq) + 2,6-DCFPT (1.2 eq)
Solvent: DCM/MeCN (2:1)
Temperature: 0°C → RT
Yield: 82-95%
            

3. Industrial Case Studies

Case 1: Anticancer Drug Intermediate

Client: Top 10 Pharma Company (USA)

• Challenge: Low yield (48%) in fluoropyrimidine synthesis
• Solution: Replaced XtalFluor-E with 2,6-DCFPT
• Result: 89% yield, 99.5% HPLC purity

Case 2: OLED Material Production

Client: Advanced Materials Manufacturer (Japan)

• Challenge: Side reactions in fluorinated emitter synthesis
• Solution: Optimized stoichiometry (1:1.05 reagent ratio)
• Result: 94% conversion, reduced purification steps

4. Technical Support & Inquiry

Our chemical engineers provide:

• Custom synthesis protocols
• Bulk order optimization (100g-100kg scale)
• Regulatory documentation support

Contact our specialists:

info@vivalr.com
(86) 15866781826