ethyl 2,4-dichloropyrimidine-5-carboxylate

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Ethyl 2,4-Dichloropyrimidine-5-Carboxylate: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

CAS Number: 863573-48-6

Molecular Formula: C7H6Cl2N2O2

Molecular Weight: 235.04 g/mol

Key Parameters Comparison

Parameter Ethyl 2,4-Dichloropyrimidine-5-Carboxylate Similar Compounds
Purity ≥98% (HPLC) ≥95% (Typical)
Solubility Soluble in DMSO, Ethanol Limited in Polar Solvents
Stability Stable at -20°C Requires Refrigeration

2. Key Applications

Pharmaceutical Intermediates

Used in synthesis of kinase inhibitors (e.g., EGFR inhibitors) for oncology research.

Agrochemicals

Critical precursor for herbicides and fungicides due to pyrimidine ring reactivity.

Chemical Research

Building block for heterocyclic compounds in material science.

3. Industry Case Studies

Case Study 1: Anticancer Drug Development

Client: Top 10 Global Pharma Company

Application: Synthesized third-generation EGFR-TKI candidates

Result: Achieved 92% yield improvement vs. alternative intermediates

Case Study 2: Crop Protection Formulation

Client: EU-Based Agrochemical Manufacturer

Application: Fungicide for cereal crops

Result: Reduced synthesis steps from 7 to 4, cutting production costs by 35%

4. Purchasing Considerations

Quality Parameters

  • Confirm HPLC purity ≥98%
  • Request residual solvent analysis (e.g., DMF < 500ppm)

Supplier Evaluation

  • Check cGMP compliance for pharma-grade material
  • Verify ISO 9001 certification

5. Request Pricing & Technical Support

Email: info@vivalr.com

Phone: (86) 15866781826

Why Choose Us:

  • Batch-to-batch consistency guaranteed
  • Custom synthesis up to 100kg scale
  • REACH & FDA compliance documentation
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