Comprehensive Guide to 2-Cyano-5-fluoropyridine
Table of Contents
- 1. Product Overview
- 2. Parameter Comparison
- 3. Key Applications
- 4. Usage Cases
- 5. Client Case Studies
- 6. Request a Quote
1. Product Overview
2-Cyano-5-fluoropyridine (CAS 374633-01-9) is a fluorinated pyridine derivative widely used in pharmaceuticals, agrochemicals, and material science. Key specifications include:
| Parameter | Value |
|---|---|
| Molecular Formula | C6H3FN2 |
| Molecular Weight | 138.11 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Melting Point | 72-75°C |
| Storage | 2-8°C in airtight container |
2. Parameter Comparison
| Compound | Melting Point | Reactivity | Typical Purity |
|---|---|---|---|
| 2-Cyano-5-fluoropyridine | 72-75°C | High (CN/F groups) | ≥98% |
| 2-Cyano-3-fluoropyridine | 68-70°C | Moderate | ≥95% |
| 5-Fluoro-2-methylpyridine | N/A (liquid) | Low | ≥90% |
3. Key Applications
Pharmaceutical Intermediates
Used in synthesis of kinase inhibitors, antiviral agents, and CNS drugs due to its electron-withdrawing groups.
Agrochemicals
Key component in next-gen herbicides and fungicides requiring fluorine-enhanced bioavailability.
Material Science
Building block for liquid crystals and conductive polymers in OLED displays.
4. Usage Cases
Case 1: Anticancer Drug Synthesis
Step 1: React with boronic acid under Suzuki conditions
Step 2: Catalytic hydrogenation of nitrile group
Yield: 82% over two steps
Case 2: Herbicide Formulation
10% concentration in non-systemic herbicides showed 94% weed suppression in field trials.
5. Client Case Studies
PharmaTech Solutions (Germany)
Challenge: Required high-purity fluoropyridine derivative for Phase III clinical trial materials
Solution: Supplied 50kg batches at 99.2% purity
Result: Accelerated API production by 6 weeks
AgroChem Solutions (USA)
Challenge: Needed cost-effective fluorinated building block for new herbicide line
Solution: Custom synthesis at 1/3 market price
Result: Launched product 4 months ahead of schedule
6. Request a Quote
Contact our technical team for pricing, COA, or custom synthesis requirements:
Email: info@vivalr.com
Phone: (86) 15866781826
Response within 2 working hours


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