3-Phenylpyridine: Comprehensive Technical Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 1008-88-4 |
| Molecular Formula | C11H9N |
| Appearance | Colorless oily liquid |
| Purity | ≥99% (Pharmaceutical Grade) |
| Density | 1.082 g/mL at 25°C |
| Boiling Point | 269-270°C at 749 mmHg |
| Flash Point | >230°F (>110°C) |
2. Key Applications
3-Phenylpyridine serves as a critical intermediate in:
- Pharmaceutical synthesis (APIs and bioactive molecules)
- Agrochemical production (pesticide precursors)
- Organic electronic materials (OLED intermediates)
- Coordination chemistry (ligand for metal complexes)
3. Synthesis Methods
Optimized Production Routes
| Method | Reactants | Yield | Advantages |
|---|---|---|---|
| Suzuki Coupling | 3-Iodopyridine + Phenylboronic Acid | 97% | High selectivity, mild conditions |
| Direct Arylation | Pyridine + Benzene Derivatives | 93% | Cost-effective for bulk production |
4. Safety & Handling
| Hazard Code | Risk Phrases | Preventive Measures |
|---|---|---|
| Xi | H315-H319-H335 | Use NIOSH-approved PPE, ensure proper ventilation |
Storage: Keep container tightly closed in cool, dry place (2-8°C)
5. Industrial Case Studies
Case 1: Pharmaceutical Intermediate Production
Client: Top 10 Global API Manufacturer
Application: Synthesis of antiviral drug intermediate
Result: 22% cost reduction vs traditional routes
Case 2: OLED Material Development
Client: Leading Display Technology Company
Application: Electron transport layer material
Result: Achieved 15% efficiency improvement
6. Contact for Technical Support
For product specifications, SDS, or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
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