5-Fluoro-2-methoxynicotinaldehyde: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
5-Fluoro-2-methoxynicotinaldehyde (CAS 1209408-12-3) is a fluorinated nicotinaldehyde derivative with the molecular formula C8H6FNO2 and a molecular weight of 167.14 g/mol. This heterocyclic compound is widely used as a key intermediate in pharmaceuticals and agrochemicals.
Key Parameters & Comparison
| Parameter | 5-Fluoro-2-methoxynicotinaldehyde | 2-Methoxynicotinaldehyde |
|---|---|---|
| Purity | ≥98% (HPLC) | ≥95% |
| Melting Point | 72-75°C | 68-70°C |
| Fluorine Content | 11.37% | 0% |
*Fluorination enhances metabolic stability in API synthesis.
2. Applications & Use Cases
Pharmaceutical Intermediates
Used in synthesizing kinase inhibitors and antiviral agents. The fluorine atom improves bioavailability and target binding affinity.
Agrochemical Development
Critical for creating herbicidal compounds with enhanced leaf permeability due to its lipophilic properties.
Chemical Research
Acts as a building block for fluorescent probes in bioimaging studies.
3. Industry Case Studies
Case 1: Antiviral Drug Development
Client: Tier-1 European Pharma Company
Application: Synthesis of RNA polymerase inhibitor intermediates
Result: Achieved 92% yield in palladium-catalyzed coupling reactions.
Case 2: Herbicide Formulation
Client: Agrochemical Manufacturer (USA)
Application: Development of systemic herbicides
Result: 40% improvement in rainfastness compared to non-fluorinated analogs.
Case 3: OLED Material Research
Client: Asian Electronics Conglomerate
Application: Electron-transport layer components
Result: Enhanced device lifetime by 15% at 1000 cd/m² luminance.
4. Technical Support & Inquiry
Request custom synthesis or bulk pricing:
info@vivalr.com
(86) 15866781826
MSDS and COA available upon request. Global shipping with cold-chain support.
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