Tetrahydro-2H-pyran-4-carboxylic acid

Comprehensive Guide to Tetrahydro-2H-pyran-4-carboxylic Acid

Table of Contents

• Product Overview & Specifications
• Key Applications & Use Cases
• Industry Case Studies
• Usage Guidelines
• Contact for Custom Solutions

Product Specifications

Chemical Name: Tetrahydro-2H-pyran-4-carboxylic acid

CAS Number: 5337-03-9

Molecular Formula: C₆H₁₀O₃

Molecular Weight: 130.14 g/mol

Appearance: White crystalline powder

Purity: ≥98% (HPLC)

Solubility: Soluble in water, methanol, DMSO

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Industrial Applications

Pharmaceutical Intermediates

Critical component in antiviral drug synthesis, particularly for protease inhibitors targeting RNA viruses.

Organic Synthesis

Key chiral building block for asymmetric catalysis in complex molecule assembly.

Material Science

Used in polymer modification for enhanced thermal stability in specialty coatings.

Industry Implementations

Case 1: Antiviral Drug Development

Client: Top 10 Global Pharma Company

Challenge: Required high-purity (>99%) chiral intermediate for COVID-19 therapeutic

Solution: Custom synthesis with strict impurity profile control

Outcome: Accelerated Phase III trials by 8 months

Case 2: Advanced Material Research

Client: European Research Consortium

Application: Liquid crystal precursor synthesis

Technical Requirements: Batch-to-batch consistency in optical purity

Result: Achieved 99.7% enantiomeric excess consistently

Operational Protocols

Safety Handling

• PPE Requirements: Nitrile gloves, safety goggles
• Ventilation: Use fume hood for powder handling

Storage Conditions

• Temperature: 2-8°C in airtight container
• Shelf Life: 24 months when properly stored

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