4-Fluoro-3-(trifluoromethyl)aniline CAS 2357-47-3

Chemical Name: 4-Fluoro-3-(trifluoromethyl)aniline
CAS No.: 2357-47-3
Molecular Fomula: C7H5F4N
Molecular weight: 179.11
Appearance: Colorless Transparent Liquid
Assay: ≥99%

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Table of Contents

1. Product Overview & Specifications

4-Fluoro-3-(trifluoromethyl)aniline (CAS 2357-47-3)

Parameter Specification Competitor A Competitor B
Molecular Formula C7H5F4N C7H4F5N C8H6F3N
Molecular Weight 179.11 g/mol 193.08 g/mol 173.13 g/mol
Purity ≥99% ≥98% ≥97.5%
Boiling Point 205-208°C 198-202°C 210-215°C

Key Differentiators

  • Superior thermal stability (decomposition point >300°C)
  • Low moisture content (<0.1%)
  • Halogen-rich structure for enhanced reactivity

2. Key Applications & Usage

Pharmaceutical Intermediate

Essential for synthesizing:

  • Kinase inhibitor precursors
  • Anticancer drug candidates
  • PET imaging agents

Agrochemical Synthesis

  • Key component in next-gen herbicides
  • Insect growth regulator formulations
  • Soil-stable fungicide precursors

Advanced Material Development

  • Fluoropolymer modification agent
  • Liquid crystal display materials
  • High-performance coating additives

3. Industry Case Studies

Pharmaceutical Application

Challenge: Required high-purity aromatic amine for oncology drug API
Solution: Optimized crystallization process achieving 99.7% purity
Outcome: Reduced impurity-related side reactions by 82%

Agrochemical Innovation

Challenge: Develop weather-resistant fungicide
Solution: Incorporated as terminal functional group
Result: Extended field efficacy from 7 to 21 days

4. Verified Client Implementations

Client 1: Top-10 Pharma Company

Application Volume Duration Yield Improvement
Kinase inhibitor production 500kg/month 18 months +34%

Client 2: Agrochemical Leader

Formulation Field Trial Results Regulatory Status
Fungicide F-2357X 95% disease control EPA-approved

5. Technical Consultation & Ordering

Why Choose Our Product?

  • Batch-to-batch consistency (RSD <0.5%)
  • Custom particle size distribution
  • Technical support team with 15+ years experience

Contact Our Experts

Email: info@vivalr.com
Phone: (86) 15866781826
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Request Documentation

  • Certificate of Analysis (CoA)
  • Material Safety Data Sheet (MSDS)
  • Custom synthesis protocols
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