1,2-Dimyristoyl-sn-glycero-3-phosphocholine CAS 18194-24-6
Chemical Name: 1,2-Dimyristoyl-sn-glycero-3-phosphocholine（DMPC）
Synonyms: sn-3-Dimyristoyllecithin; DMPC
CAS No.: 18194-24-6
Molecular Fomula: C36H72NO8P
Molecular weight: 677.93
Appearance: white crystalline powder
Assay: ≥99.0%
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (CAS 18194-24-6): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Key Parameters
| Parameter | Value |
|---|---|
| CAS Number | 18194-24-6 |
| Molecular Formula | C36H72NO8P |
| Molecular Weight | 678.93 g/mol |
| Appearance | White to off-white powder |
| Purity | ≥99% (HPLC) |
| Storage | -20°C, desiccated |
Comparative Analysis
| Property | DMPC | DPPC | DSPC |
|---|---|---|---|
| Phase Transition Temp. | 23°C | 41°C | 55°C |
| Chain Length | C14:0 | C16:0 | C18:0 |
| Applications | Drug delivery, membrane studies | High-temp formulations | Long-circulating liposomes |
2. Applications & Use Cases
Primary Applications
- Liposomal Drug Delivery: Enhances encapsulation efficiency of hydrophobic APIs
- Membrane Biophysics: Ideal for constructing model lipid bilayers
- Cosmetic Formulations: Improves skin permeability of active ingredients
- Diagnostic Reagents: Stabilizes protein-lipid interactions in assays
3. Step-by-Step Usage Guidelines
Liposome Preparation Protocol
- Dissolve 10 mg DMPC in chloroform (2 mL)
- Evaporate solvent under nitrogen to form thin film
- Hydrate with PBS buffer (pH 7.4) at 45°C
- Extrude through 100 nm polycarbonate membrane
- Characterize via dynamic light scattering
4. Real-World Customer Case Studies
Case 1: Novartis AG
Challenge: Improve solubility of oncology drug candidate
Solution: DMPC-based liposomes increased bioavailability by 300%
Result: Successful Phase I clinical trial completion
Case 2: L’Oréal Research
Challenge: Enhance retinol stability in anti-aging cream
Solution: 2% DMPC formulation reduced oxidative degradation
Result: 18-month shelf life achievement
5. Technical Support & Inquiry
For bulk orders or technical queries:
Email: info@vivalr.com
Phone: (86) 15866781826
Request Custom Quote
Submit your requirements for:
– Bulk pricing
– Regulatory documentation
– Stability testing data
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