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3-Amino-4-bromopyridine: Comprehensive User Guide for Industrial Applications
Table of Contents
1. Product Overview & Technical Specifications
| Parameter | 3-Amino-4-bromopyridine | Similar Compound (3-Amino-5-bromopyridine) |
|---|---|---|
| CAS Number | 13534-09-1 | 13534-08-0 |
| Molecular Formula | C5H5BrN2 | C5H5BrN2 |
| Purity | ≥98% (HPLC) | ≥95% |
| Solubility | Soluble in DMSO, Methanol | Limited in polar solvents |
2. Industrial Applications & Functional Uses
2.1 Pharmaceutical Intermediates
Widely used in synthesis of kinase inhibitors and oncology drugs due to its unique bromine substitution pattern.
2.2 Organic Synthesis
Key building block for cross-coupling reactions (Buchwald-Hartwig amination, Suzuki-Miyaura).
2.3 Agrochemical Development
Essential component in novel pesticide formulations targeting resistant insect species.
3. Operational Protocols & Best Practices
Case Study: Anticancer Drug Synthesis
Step 1: Dissolve 5g in anhydrous DMSO (50ml) under nitrogen atmosphere
Step 2: Add Pd(PPh3)4 catalyst (0.5mol%)
Step 3: React with aryl boronic acid at 80°C for 12h (yield: 82-85%)
4. Verified Customer Implementations
4.1 Top-10 Pharma Company (EU)
Application: PARP inhibitor development
Result: Achieved 40% improvement in reaction yield compared to alternative bromopyridines
4.2 Agrochemical Leader (USA)
Application: Neonicotinoid derivative synthesis
Result: Developed patent-pending insecticide with 99% pest mortality rate
4.3 University Research Lab (Japan)
Application: OLED material research
Result: Created novel electron-transport layer with 15% efficiency gain
5. Contact Our Technical Experts
Email: info@vivalr.com
Phone: (86) 15866781826
Request free sample or technical dossier:
- Batch-specific COA available
- Custom synthesis options
- GMP-grade quantities (100kg+)
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