Methyl 2,4-Dichloropyrimidine-6-Carboxylate: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Methyl 2,4-Dichloropyrimidine-6-Carboxylate is a specialized pyrimidine derivative widely used in pharmaceutical and agrochemical research. Key specifications include:
| Parameter | Details |
|---|---|
| CAS Number | 87600-71-3 (structural analog reference) |
| Molecular Formula | C7H5Cl2N2O2 |
| Molecular Weight | 220.03 g/mol |
| Purity | ≥95% (HPLC) |
Note: Custom synthesis and purity grades available upon request.
2. Key Applications
This compound serves as a critical intermediate in:
- Pharmaceutical synthesis (e.g., antiviral and anticancer drug development)
- Agrochemical production (herbicide and pesticide precursors)
- Organic electronics (semiconductor material research)
- Protecting group strategies in nucleoside chemistry
3. Usage Guidelines
Handling & Storage
- Store at 2–8°C in airtight containers
- Use under inert gas (N2 or Ar) for moisture-sensitive reactions
Reaction Optimization
- Typical coupling conditions: 0.1–1.0 eq in DMF/DCM at 0–25°C
- Compatible with Suzuki-Miyaura and Buchwald-Hartwig cross-couplings
4. Case Studies
Case 1: Antiviral Drug Intermediate
A research team successfully utilized this compound to synthesize a novel non-nucleoside reverse transcriptase inhibitor, achieving 78% yield in the key coupling step.
Case 2: Herbicide Development
Derivatization of the pyrimidine core enabled creation of a herbicidal agent with 90% weed suppression efficacy at 50 ppm concentration.
5. Client Success Stories
| Client | Application | Outcome |
|---|---|---|
| Shanghai PharmaTech | Oncology candidate synthesis | Reduced synthesis steps from 8 to 5 |
| EuroAgro Solutions | Next-gen herbicide development | Field trial success in 3 countries |
6. Request a Quote
For pricing, bulk orders, or technical support:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Custom synthesis and analytical data packages available.


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