5-Amino-2-bromo-3-methylpyridine

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5-Amino-2-bromo-3-methylpyridine User Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 113118-15-9
Molecular Formula C6H7BrN2
Molecular Weight 187.04 g/mol
Appearance White to light brown crystalline powder
Purity ≥98% (HPLC)
Storage Conditions 2-8°C in dark, dry environment

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Critical building block for antiviral agents (e.g., HIV protease inhibitors) and kinase inhibitors targeting cancer pathways.

Agrochemical Synthesis

Key precursor in neonicotinoid insecticides and fungicide development through Buchwald-Hartwig cross-coupling reactions.

Material Science

Coordination ligand for transition metal catalysts in OLED material development and polymer modification.

3. Comparative Analysis with Similar Compounds

Compound 5-Amino-2-bromo-3-methylpyridine 5-Amino-2-chloro-3-methylpyridine 5-Amino-3-methylpyridine
Reactivity High (Bromine leaving group) Moderate Low
Cross-coupling Efficiency 92-95% yield 85-88% yield N/A
Price Competitiveness $$$ $$ $

4. Industry Case Studies

Case 1: Anticancer Drug Development

Used as key intermediate in third-generation BTK inhibitor synthesis, achieving 98.7% purity in final API crystallization.

Case 2: OLED Material Production

Enabled 15% efficiency improvement in blue-emitting materials through optimized ligand-metal coordination.

5. Client Success Stories

ABC Pharmaceuticals (Frankfurt, Germany)

“Achieved 40% cost reduction in our kinase inhibitor production using VIVALR’s brominated pyridine derivatives.”

ChemInnovate Solutions (Boston, USA)

“Technical support team helped optimize Suzuki coupling conditions, increasing batch yield from 78% to 93%.”

6. Request Customized Solutions

Contact our technical team for:

  • Custom synthesis scale-up (kg to ton quantities)
  • Regulatory support (REACH, FDA DMF filings)
  • Application-specific purity optimization

Email: info@vivalr.com
Tel: (86) 15866781826

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