Methyl 6-Chloropyridazine-3-carboxylate: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Methyl 6-Chloropyridazine-3-carboxylate (CAS 33252-28-7) is a high-purity chemical intermediate widely used in pharmaceuticals and agrochemicals. Key parameters:
| Parameter | Specification |
|---|---|
| Molecular Formula | C7H5ClN2O2 |
| Molecular Weight | 200.58 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Storage | 2-8°C in airtight container |
2. Applications & Use Cases
Pharmaceutical Intermediates
Used in synthesis of kinase inhibitors and antiviral agents due to its pyridazine backbone.
Agrochemical Synthesis
Key precursor for herbicides and fungicides, enabling selective chlorination reactions.
Organic Chemistry Research
Employed in cross-coupling reactions (e.g., Suzuki-Miyaura) for heterocyclic compound development.
3. Customer Case Studies
Case 1: Top 10 Pharma Company (EU)
Challenge: Low yield (42%) in JAK1 inhibitor intermediate synthesis.
Solution: Optimized reaction using Methyl 6-Chloropyridazine-3-carboxylate as coupling agent.
Result: Yield increased to 78%, reduced purification steps.
Case 2: Agrochemical Manufacturer (USA)
Challenge: Impurity control in fungicide precursor.
Solution: Implemented recrystallization protocol with ≥98% purity grade.
Result: Achieved 99.2% HPLC purity, reduced batch rejection by 90%.
4. Technical Comparison
| Vendor | Purity | Packaging | Lead Time |
|---|---|---|---|
| Vivalr Chemicals | 98-99% | 1kg, 5kg, custom | 2 weeks |
| Competitor A | 95-97% | 100g only | 6 weeks |
| Competitor B | 90-92% | 25kg bulk | 8 weeks |
5. Contact for Quotation
Request bulk pricing or technical documents:
Email: info@vivalr.com
Phone: (86) 15866781826
ISO 9001-certified production | GC/MS batch analysis available | 24h response time
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10. Proper chemical nomenclature and CAS reference
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