2-Methyl-4-nitropyridine

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2-Methyl-4-nitropyridine Buyer’s Guide & Industry Applications (2024)

Parameter	Specification
CAS Number	4214-79-3
Molecular Formula	C6H6N2O2
Molecular Weight	138.12 g/mol
Appearance	Light yellow crystalline powder
Purity (HPLC)	≥99.0%
Melting Point	38-42°C
Boiling Point	285.3±23.0°C (760 mmHg)
Density	1.25±0.1 g/cm³
Storage Conditions	2-8°C in inert atmosphere
HS Code	2933399090

Compound	Reactivity	Thermal Stability	Pharma Compatibility	Cost Efficiency
2-Methyl-4-nitropyridine	High	Moderate	Excellent	$$$
4-Nitropyridine	Medium	Low	Good	$$
2-Chloro-4-nitropyridine	Very High	Poor	Limited	$$$$

Key roles in synthesizing:

Parameter	Requirement
Personal Protection	Chemical goggles, nitrile gloves, respirator
Ventilation	LEV system with ≥0.5 m/s capture velocity
Spill Management	Neutralize with 10% sodium bicarbonate
Incompatibilities	Strong oxidizers, concentrated acids

Client: Top-10 Global Pharma Company

Application: Third-stage intermediate in PARP inhibitor synthesis

Outcome: 22% yield improvement vs. previous synthesis route

Client: EU Agrochemical Manufacturer

Application: Key chiral building block for ALS inhibitors

Result: Achieved 99.8% enantiomeric excess

For batch customization or technical queries:

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类别 chem