2-Chloromethyl-4-methoxy-3,5-dimethylpyridine hydrochloride

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2-Chloromethyl-4-methoxy-3,5-dimethylpyridine Hydrochloride: Technical Guide

1. Product Overview & Specifications

Parameter Specification
CAS Number 86604-75-3
Chemical Formula C9H13Cl2NO
Molecular Weight 234.12 g/mol
Synonyms Omeprazole EP Impurity XI, CMDM, Chloromethylpyridine Hydrochloride
Appearance White to off-white crystalline powder
Purity ≥99% (HPLC)

2. Key Applications

This intermediate is critical for:

  • Proton Pump Inhibitors (PPIs): Core building block for Omeprazole and Esomeprazole synthesis
  • Pharmaceutical Intermediates: Used in API production under GMP conditions
  • Research Chemicals: Reference standard for impurity profiling in drug development

3. Usage Guidelines

Storage Conditions

  • Temperature: 2-8°C in sealed containers
  • Protect from moisture and light exposure

Handling Precautions

  • Use PPE including nitrile gloves and safety goggles
  • Handle in well-ventilated areas or fume hoods

4. Industry Case Studies

Case 1: Large-Scale API Production

Client: Major Chinese pharmaceutical manufacturer
Application: Annual production of 50MT Omeprazole using this intermediate
Result: Achieved 99.8% purity in final API batches

Case 2: European Drug Development

Client: EU-based research institute
Application: Synthesis of novel PPI derivatives
Result: Successful IND submission with complete impurity profile documentation

5. Technical Inquiry

For COA, pricing, or custom synthesis requirements:

Provide your organization name, intended use, and required quantity for fastest response.

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