Trimethylacetonitrile (CAS 630-18-2) Buyer’s Guide: Applications, Case Studies & Supplier Insights
Table of Contents
- Product Overview & Specifications
- Key Applications & Industrial Uses
- Technical Comparison of Commercial Grades
- Safety & Handling Protocols
- Industry Application Case Studies
- Procurement Guidance & Supplier Evaluation
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 630-18-2 |
| Chemical Name | 2,2-Dimethylpropionitrile |
| Molecular Formula | C5H9N |
| Purity Grades | Industrial (98%), Pharmaceutical (99.5%), Research (99.9%) |
| Boiling Point | 102-104°C |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate
Critical precursor for ACE inhibitors and CNS drugs requiring high-purity nitrile compounds.
Agrochemical Synthesis
Key building block in pyrethroid insecticides and herbicide formulations.
Advanced Material Production
Used in specialty polymers and liquid crystal displays requiring precise molecular structures.
3. Technical Comparison of Commercial Grades
| Grade | Purity | Typical Use | Price Range (USD/kg) |
|---|---|---|---|
| Industrial | 98% | Bulk chemical synthesis | $45-65 |
| Pharmaceutical | 99.5% | API production | $120-180 |
| Research | 99.9% | Laboratory R&D | $250-400 |
4. Safety & Handling Protocols
GHS Classification
- Acute Toxicity (Category 3)
- Skin Irritation (Category 2)
Protective Measures
Required PPE: Chemical-resistant gloves, vapor respirators, and full-face protection during transfers.
5. Industry Application Case Studies
Case 1: Cardiovascular Drug Manufacturing
Client: European Pharma Leader
Challenge: Required 99.7% purity with strict residual solvent limits
Solution: Custom purification process achieving <0.1% solvent residues
Outcome: Successful FDA approval of antihypertensive medication
Case 2: Next-Gen Pesticide Development
Client: Asian Agrochemical Innovator
Challenge: Needed stable nitrile source for weather-resistant formulation
Solution: Specialty stabilized grade with antioxidant additives
Outcome: 30% improvement in field efficacy under tropical conditions
6. Procurement Guidance & Supplier Evaluation
Quality Verification
- Request batch-specific GC-MS reports
- Verify ISO 9001 certification status
Supplier Checklist
| Criterion | Requirement |
|---|---|
| Minimum Order Quantity | <100kg for R&D projects |
| Lead Time | <4 weeks for standard grades |
Contact for Technical Consultation
Email: info@vivalr.com
Phone: (86) 15866781826
Request: Custom synthesis capabilities available for bulk orders >500kg



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