Trimethylacetonitrile CAS 630-18-2

Chemical Name: Trimethylacetonitrile
CAS No.: 630-18-2
Molecular Fomula: C5H9N
Molecular weight: 83.13
Appearance: Transparent colorless liquid
Assay: ≥99%

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Trimethylacetonitrile (CAS 630-18-2) Buyer’s Guide: Applications, Case Studies & Supplier Insights

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 630-18-2
Chemical Name 2,2-Dimethylpropionitrile
Molecular Formula C5H9N
Purity Grades Industrial (98%), Pharmaceutical (99.5%), Research (99.9%)
Boiling Point 102-104°C

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Critical precursor for ACE inhibitors and CNS drugs requiring high-purity nitrile compounds.

Agrochemical Synthesis

Key building block in pyrethroid insecticides and herbicide formulations.

Advanced Material Production

Used in specialty polymers and liquid crystal displays requiring precise molecular structures.

3. Technical Comparison of Commercial Grades

Grade Purity Typical Use Price Range (USD/kg)
Industrial 98% Bulk chemical synthesis $45-65
Pharmaceutical 99.5% API production $120-180
Research 99.9% Laboratory R&D $250-400

4. Safety & Handling Protocols

GHS Classification

  • Acute Toxicity (Category 3)
  • Skin Irritation (Category 2)

Protective Measures

Required PPE: Chemical-resistant gloves, vapor respirators, and full-face protection during transfers.

5. Industry Application Case Studies

Case 1: Cardiovascular Drug Manufacturing

Client: European Pharma Leader
Challenge: Required 99.7% purity with strict residual solvent limits
Solution: Custom purification process achieving <0.1% solvent residues
Outcome: Successful FDA approval of antihypertensive medication

Case 2: Next-Gen Pesticide Development

Client: Asian Agrochemical Innovator
Challenge: Needed stable nitrile source for weather-resistant formulation
Solution: Specialty stabilized grade with antioxidant additives
Outcome: 30% improvement in field efficacy under tropical conditions

6. Procurement Guidance & Supplier Evaluation

Quality Verification

  • Request batch-specific GC-MS reports
  • Verify ISO 9001 certification status

Supplier Checklist

Criterion Requirement
Minimum Order Quantity <100kg for R&D projects
Lead Time <4 weeks for standard grades

Contact for Technical Consultation

Email: info@vivalr.com
Phone: (86) 15866781826
Request: Custom synthesis capabilities available for bulk orders >500kg

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